Medicine : Zymurine (50mg)

Name:Zymurine (50mg)
Manufacturer:Zydus Cadila
Generic Use:Azathioprine
Composition:Azathioprine(50 Mg)
Substitutes:zinothin (50mg) , immuzat (50mg) , imuzat (50mg) , transimune (50mg) , azimune (50mg) , azathioprine (50mg) , azoprine (50mg) , azap (50mg) , zymurine (50mg) , thiazprine (50mg) , azoran (50mg) , imuran (50mg) , azimum (50mg) , azathhioprine (50mg) , transiumne (50mg) , imuza (50mg) , aretha (50mg)

Generic ( Azathioprine )

Typical use Of Azathioprine :Renal Transplantation. Autoimmune Diseases. Severe Rheumatoid Arthritis Unresponsive To Other Drugs.
Mechanism of action of Azathioprine :Azathioprine Is An Imidazolyl Derivative Of Mercaptopurine, Which Inhibits DNA, RNA And Protein Synthesis And Antagonises Purine Synthesis. It Also Inhibits Mitosis And Interferes With Cellular Metabolism Of Susceptible Organisms. Azathioprine Inj Should Be Converted To Oral Therapy As Soon As The Drug Can Be Tolerated.
Drug Interaction of Azathioprine :Allopurinol That Is Used For Treating Increased Blood Levels Of Uric Acid And Preventing Gout Increases Azathioprine Levels In The Blood Which May Increase The Risk Of Side Effects From Azathioprine. Therefore, It Is Important To Reduce The Dose Of Azathioprine By Approximately 1/3 To 1/4 In Patients Taking Allopurinol. The Use Of Angiotensin-converting Enzyme (ACE) Inhibitors To Control High Blood Pressure In Patients Taking Azathioprine Has Been Reported To Induceanemia (low Levels Of Red Blood Cells) And Severe Leukopenia (low Levels Of White Blood Cells). Azathioprine Reduces Blood Levels Of The Blood Thinner,warfarin (Coumadin), And Thus May Reduce The Blood Thinning Effect Of Warfarin. Safety And Efficacy Of Azathioprine In Children Have Not Been Established
Side effects of Azathioprine :Fever, Chills, Bone Marrow Depression Characterised By Leucopenia, Thrombocytopenia Or Anaemia, Anorexia, Nausea, Diarrhoea, Arthralgias, Secondary Infections, Hepatotoxicity, Rash, Alopoecia.


How Azathioprine will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Azathioprine will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Azathioprine

No Studies Found