Medicine : Zoflut Skin(10gm)

Name:Zoflut Skin(10gm)
Type:Cream
Manufacturer:Cipla Ltd
Generic Use:Fluticasone Propionate , Fluticasone
Composition:Fluticasone Propionate(0.05% W/w) , Fluticasone(0.005% W/w)
Substitutes:zoflut skin(10gm) , zoflut skin(10gm)


Generic ( Fluticasone Propionate )



Typical use Of Fluticasone Propionate :Allergic Rhinitis, Asthma, Atopic Eczema, Contact Sensitivity Reactions, Dermatitis, Discoid Eczema, Discoid Lupus Erythematosus, Eczema, Infantile Eczema, Neurodermatoses, Perennial Rhinitis, Psoriasis, Purigo Nodularis, Seborrheic Dermatitis.
Mechanism of action of Fluticasone Propionate :Fluticasone Propionate Binds To The Glucocorticoid Receptor With High Affinity And Produces Alteration Of Transcription And Protein Synthesis, A Decreased Release Of Leukocytic Acid Hydrolases, Reduction In Fibroblast Proliferation, Prevention Of Macrophage Accumulation At Inflamed Sites, Reduction Of Collagen Deposition, Interference With Leukocyte Adhesion To The Capillary Wall, Reduction Of Capillary Membrane Permeability And Subsequent Edema, Reduction Of Complement Components, Inhibition Of Histamine And Kinin Release, And Interference With The Formation Of Scar Tissue.
Drug Interaction of Fluticasone Propionate :Fluticasone Propionate Is Known To Interact With Other Drugs Like Carbamazepine, Cyclosporin A, Frusemide Or Furosemide, Phenytoin (Na), Primidone, Rifampicin, Theophylline, Warfarin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Fluticasone Propionate :Glaucoma, Cataract, Growth Retardation, Adrenocortical Suppression, Decrease In Bone Mineral Density, Pruritus, Dysphonia, Allergic Contact Dermatitis, Cough, Oral Candidiasis, Local Burning, Hyperpigmentation, Hypertrichosis, Vocal Cord Myopathy, Throat Irritation, Superficial Blood Vessels Dilatation, Superficial Blood Vessels Thinning.

INTERACTIONS OF FLUTICASONE PROPIONATE


How Fluticasone Propionate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Fluticasone Propionate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Fluticasone Propionate

No Studies Found






Generic ( Fluticasone )



Typical use Of Fluticasone :Asthma, Chronic Obstructive Pulmonary Disease
Mechanism of action of Fluticasone :Fluticasone Utilises A Fluorocarbothioate Ester Linkage At The C17 Position. It Has Potent Vasoconstrictive And Anti-inflammatory Activity, But Weak HPA Inhibitory Effect When Applied Topically.
Drug Interaction of Fluticasone : Ritonavir (Norvir), Atazanavir (Reyataz),clarithromycin (Biaxin), Indinavir (Crixivan), Itraconazole (Sporanox),ketoconazole, Nelfinavir (Viracept), And Telithromycin (Ketek) May Increase Levels Of Fluticasone In The Body By Reducing The Breakdown Of Fluticasone Byliver Enzymes. This May Increase Side Effects Of Fluticasone.
Side effects of Fluticasone :Glaucoma, Cataract, Growth Retardation, Adrenocortical Suppression, Decrease In Bone Mineral Density.

INTERACTIONS OF FLUTICASONE


How Fluticasone will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Fluticasone will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Fluticasone

No Studies Found