Medicine : Zincovit (2x15)

Name:Zincovit (2x15)
Type:Tablet
Manufacturer:Apex Laboratories Pvt Ltd
Generic Use:Ascorbic Acid , Niacinamide , Tocopherol Acetate
Composition:Ascorbic Acid(75mcg) , Niacinamide(50mg) , Tocopherol Acetate(15mg)
Substitutes:zincovit (2x15) , zincovit (2x15) , zincovit (2x15)


Generic ( Ascorbic Acid )


Typical use Of Ascorbic Acid :Prevention And Treatment Of Scurvy, Scurvy, Vitamin Deficiency.
Mechanism of action of Ascorbic Acid :In Humans, An Exogenous Source Of Ascorbic Acid Is Required For Collagen Formation And Tissue Repair By Acting As A Cofactor In The Posttranslational Formation Of 4-hydroxyproline In -Xaa-Pro-Gly- Sequences In Collagens And Other Proteins. Ascorbic Acid Is Reversibly Oxidized To Dehydroascorbic Acid In The Body. These Two Forms Of The Vitamin Are Believed To Be Important In Oxidation-reduction Reactions. The Vitamin Is Involved In Tyrosine Metabolism, Conversion Of Folic Acid To Folinic Acid, Carbohydrate Metabolism, Synthesis Of Lipids And Proteins, Iron Metabolism, Resistance To Infections, And Cellular Respiration.
Drug Interaction of Ascorbic Acid :Interacts With Other Drugs Like Aminophylline, Bleomycin, Chloramphenicol, Chlorothiazide, Desogestrel, Erythromycin, Ethinyloestradiol, Hydrocortisone, Iron Salts, Levonorgestrel, Mestranol, Methylamphetamine, Nafcillin, Nitrofurantoin, Paracetamol, Rutin (Vitamin P), Sodium Bicarbonate, Sodium Succinate, Sulphadiazine.These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ascorbic Acid :Diarrhea, GI Disturbances. May Cause Acidification Of The Urine; Precipitation Of Urate, Cystine Or Oxalate Stones, Or Drugs In The Urinary Tract.

INTERACTIONS OF ASCORBIC ACID

How Ascorbic Acid will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ascorbic Acid will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ascorbic Acid

No Studies Found





Generic ( Niacinamide )


Typical use Of Niacinamide :To Treat Hartnup Disease (light Sensitive Skin Rashes), Inflammatory Skin Disease, Vitamin Deficiency, Anxiety And Alzheimer’s Disease (disorder That Causes Mental Confusion And Forgetfulness). It Is Also Used In Combination With Intravenous Vitamin C Therapy For Cancer.
Mechanism of action of Niacinamide :Niacinamide As A Nutritional Supplement Is Necessary For Tissue Respiration, Glucose Production, Lipid, Amino Acid, Protein, And Purine Metabolism In The Body. Niacinamide At Higher Doses Lowers Blood Levels Of Cholesterol And Triglyceride.
Drug Interaction of Niacinamide :Niacinamide Is Known To Interact With Other Drugs Like Carbamazepine, Clonidine, Allopurinol, Anti-diabetic Drugs, Cholesterol Lowering Drugs (cholestyramine And Atorvastatin), Primidone, Probenecid And Sulfinpyrazone. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Niacinamide :Liver Toxicity, Failure Of Bile Secretion In The Intestine (cholestasis), Blockade Of Portal Blood Vessels Due To Fibrosis (portal Fibrosis), Headache, Unusual Tiredness, Urge To Vomit (nausea), Heart Burn, Sore Throat, Dry Hair, Stiffness Of The Face And Inability To Focus.

INTERACTIONS OF NIACINAMIDE

How Niacinamide will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Niacinamide will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Niacinamide

No Studies Found





Generic ( Tocopherol Acetate )


Typical use Of Tocopherol Acetate :Cardiovascular Disease, Dementia, Haemolytic Anaemia, Hepatotoxin Poisoning, Metal Poisoning, Vitamin Deficiency, Malignant Neoplasms, Muscular Spasm, Parkinsonism, Prophylaxis And Treatment Of Angina, Retinopathy, Surgery.
Mechanism of action of Tocopherol Acetate :Vitamin E's Anti-atherogenic Activity Involves The Inhibition Of The Oxidation Of LDL And The Accumulation Of OxLDL In The Arterial Wall. It Also Appears To Reduce OxLDL-induced Apoptosis In Human Endothelial Cells. Vitamin E Inhibits Protein Kinase C (PKC) Activity. The Inhibition Of PKC Results In Inhibition Of Smooth Muscle Cell Proliferation, Which Is Involved In Atherogenesis.Vitamin E's Antithrombotic And Anticoagulant Activities Involves The Downregulation Of The Expression Of Intracellular Cell Adhesion Molecule(ICAM)-1 And Vascular Cell Adhesion Molecule(VCAM)-1 Which Lowers The Adhesion Of Blood Components To The Endothelium. Vitamin E Upregulates The Expression Of Cytosolic Phospholipase A2 And Cyclooxygenase (COX)-1 Which In Turn Enhances The Release Of Prostacyclin. Prostacyclin Is A Vasodilating Factor And Inhibitor Of Platelet Aggregation And Platelet Release. Vitamin E Has Also Been Found In Culture To Decrease Plasma Production Of Thrombin, A Protein Which Binds To Platelets And Induces Aggregation. A Metabolite Of Vitamin E Called Vitamin E Quinone Or Alpha-tocopheryl Quinone (TQ) Is A Potent Anticoagulant. This Metabolite Inhibits Vitamin K-dependent Carboxylase, Which Is A Major Enzyme In The Coagulation Cascade. Many Disorders Of The Nervous System Are Caused By Oxidative Stress. Vitamin E Protects Against This Stress, Thereby Protecting The Nervouse System.
Drug Interaction of Tocopherol Acetate :Tocopherol (Vitamin E) Is Known To Interact With Other Drugs Like Colestipol (HCl), Desogestrel, Retinol (Vitamin A), Vitamin K, Warfarin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Tocopherol Acetate :Thrombosis, Bleeding In Vitamin K Deficient Patients, Necrotizing Enterocolitis In Premature Infants, Flatulence, Weakness, Dizziness, Fatigue, Nausea, Diarrhea, Abdominal Pain, Blurred Vision, Thrombophlebitis, Myopathy, Hypertension.

INTERACTIONS OF TOCOPHEROL ACETATE

How Tocopherol Acetate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Tocopherol Acetate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Tocopherol Acetate

No Studies Found