Medicine : Xylocaine Topical(30ml)

Name:Xylocaine Topical(30ml)
Type:Syrup
Manufacturer:Astra Zeneca
Generic Use:Ethanol , Lidocaine
Composition:Ethanol(28.29v/v) , Lidocaine(100mg)
Substitutes:xylocaine topical(30ml) , xylocaine topical(30ml)


Generic ( Ethanol )



Typical use Of Ethanol :Antidote For Methanol Or Ethylene Glycol Ingestion.
Mechanism of action of Ethanol :Ethanol Affects The BrainĀs Neurons In Several Ways. It Alters Their Membranes As Well As Their Ion Channels, Enzymes, And Receptors. Alcohol Also Binds Directly To The Receptors For Acetylcholine, Serotonin, GABA, And The NMDA Receptors For Glutamate. The Sedative Effects Of Ethanol Are Mediated Through Binding To GABA Receptors And Glycine Receptors (alpha 1 And Alpha 2 Subunits). It Also Inhibits NMDA Receptor Functioning. In Its Role As An Anti-infective, Ethanol Acts As An Osmolyte Or Dehydrating Agent That Disrupts The Osmotic Balance Across Cell Membranes.
Drug Interaction of Ethanol :Ethanol Is Known To Interact With Other Drugs Like Abacavir, Gabapentin Enacarbil, Mipomersen, Tizanidine, Triprolidine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ethanol :Emotional Lability, Visual Impairment, Slurred Speech, Ataxia (low To Moderate Concentrations), Hangover Effects Eg, Nausea, Headache, Dizziness, Tremor, Lethargy, Amnesia, Hypothermia, Hypoglycaemia (particularly In Children), Stupor, Coma, Resp Depression, Cardiomyopathy, Hypertension, CV Collapse Damage To Brain And Liver Which May Lead To Wernike-Korsakoff Syndrome (chronic Excessive Alcohol Consumption).

INTERACTIONS OF ETHANOL


How Ethanol will impact on Pregnancy ?

The Drug Should Not Be Used By Pregnant Women. Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown High Risk To Fetus. The Risk Of Drug Use In Pregnant Women Outweighs The Benefit.

How Ethanol will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ethanol

No Studies Found






Generic ( Lidocaine )



Typical use Of Lidocaine :Information Not Available.
Mechanism of action of Lidocaine :Lidocaine Stabilizes The Neuronal Membrane By Inhibiting The Ionic Fluxes Required For The Initiation And Conduction Of Impulses Thereby Effecting Local Anesthetic Action. Lidocaine Alters Signal Conduction In Neurons By Blocking The Fast Voltage Gated Sodium (Na+) Channels In The Neuronal Cell Membrane That Are Responsible For Signal Propagation. With Sufficient Blockage The Membrane Of The Postsynaptic Neuron Will Not Depolarize And Will Thus Fail To Transmit An Action Potential. This Creates The Anaesthetic Effect By Not Merely Preventing Pain Signals From Propagating To The Brain But By Aborting Their Birth In The First Place.
Drug Interaction of Lidocaine :Lignocaine Is Known To Interact With Other Drugs Like Alcuronium (Cl), Amphotericin B, Amprenavir, Atracurium (Besylate), Cimetidine (HCl), Edrophonium (Cl), Enflurane, Fosphenytoin, Halothane, Nadolol, Oxprenolol (HCl), Pentazocine, Propafenone (HCl). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Lidocaine :Allergy, Hypotension, Bronchospasm, Coma, Seizures, Hypertension, Tissue Necrosis, Angina, Sinus Bradycardia, Respiratory Depression, Blurred Vision, Tremors, Respiratory Depression, Bradycardia, Convulsions, Hypersensitivity, Cardiac Arrest, CNS Toxicity, Dizziness, Headache, Drowsiness, Nausea, Vomiting, Anxiety, Restlessness, Palpitation, Nervousness, Tinnitus, Abdominal Pain, Confusion.

INTERACTIONS OF LIDOCAINE


How Lidocaine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Lidocaine will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Lidocaine

No Studies Found