Medicine : Wycort Skin(5gm)

Name:Wycort Skin(5gm)
Type:Cream
Manufacturer:Wyeth India
Generic Use:Hydrocortisone Acetate , Neomycin Sulphate
Composition:Hydrocortisone Acetate(0.5%w /w) , Neomycin Sulphate(0.5%w /w)
Substitutes:wycort skin(5gm) , wycort skin(5gm)


Generic ( Hydrocortisone Acetate )



Typical use Of Hydrocortisone Acetate :Adrenal Insufficiency, Anaphylactic Reactions, Apthous Ulcers, Atopic Eczema, Collagen Disease, Congenital Adrenal Hyperplasia, Contact Allergic Dermatitis, Discoid Eczema, Flexural Psoriasis, Graft Rejection, Hypercalcaemia, Infantile Eczema, Inflammation, Irritant Dermatitis, Itching, Joint Inflammation.
Mechanism of action of Hydrocortisone Acetate :Hydrocortisone Is A Corticosteroid Used For Its Anti-inflammatory And Immunosuppressive Effects. Its Anti-inflammatory Action Is Due To The Suppression Of Migration Of Polymorphonuclear Leukocytes And Reversal Of Increased Capillary Permeability. It May Also Be Used As Replacement Therapy In Adrenocortical Insufficiency.
Drug Interaction of Hydrocortisone Acetate :Adrenal Insufficiency, Anaphylactic Reactions, Apthous Ulcers, Atopic Eczema, Collagen Disease, Congenital Adrenal Hyperplasia, Contact Allergic Dermatitis, Discoid Eczema, Flexural Psoriasis, Graft Rejection, Hypercalcaemia, Infantile Eczema, Inflammation, Irritant Dermatitis, Itching, Joint Inflammation.
Side effects of Hydrocortisone Acetate :Convulsions, Gi Bleeding, Telangiectasia, Striae, Glaucoma, Cataract, Pancreatitis, Hypersensitivity Reactions, Osteoporosis, Psychosis, Increased Intracranial Pressure, Growth Retardation, Glucose Intolerance, Epidermal Thinning, Vertebral Fractures, Avascular Necrosis, Papilloedema, Opthalmic Fungal Or Viral Disease, Dendritic Corneal Ulcers, Thromboembolic Disorder, Long Bone Fractures, Hypokalemic Alkalosis, Reduced Visual Function, Tendon Rupture.

INTERACTIONS OF HYDROCORTISONE ACETATE


How Hydrocortisone Acetate will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Hydrocortisone Acetate will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Hydrocortisone Acetate

No Studies Found






Generic ( Neomycin Sulphate )



Typical use Of Neomycin Sulphate :Decontamination Of Digestive Tract, Hepatic Coma, Hepatic Encephalopathy, Pre-operative Bowel Sterilization, Sepsis, Skin Infections
Mechanism of action of Neomycin Sulphate :Neomycin Irreversibly Bind To Specific 30S-subunit Proteins And 16S RRNA. Specifically Neomycin Binds To Four Nucleotides Of 16S RRNA And A Single Amino Acid Of Protein S12. This Interferes With Decoding Site In The Vicinity Of Nucleotide 1400 In 16S RRNA Of 30S Subunit. This Region Interacts With The Wobble Base In The Anticodon Of TRNA. This Leads To Interference With The Initiation Complex, Misreading Of MRNA So Incorrect Amino Acids Are Inserted Into The Polypeptide Leading To Nonfunctional Or Toxic Peptides And The Breakup Of Polysomes Into Nonfunctional Monosomes.
Drug Interaction of Neomycin Sulphate :Neomycin Is Known To Interact With Other Drugs Like Acarbose, Atracurium (Besylate), Cyanocobalamin, Digoxin, Doxacurium, Fluorouracil, Gentamicin, Gestodene, Hydroxocobalamin, Mecobalamin, Methotrexate, Pancuronium (Br). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Neomycin Sulphate :Urticaria, Angioneurotic Edema, Ototoxicity, Blood Dyscrasias, Anaphylactic Shock, Renal Failure, Vertigo, Headache, Diarrhea, Tinnitus, Pruritus, Lethargy, Skin Rash, Contact Dermatitis.

INTERACTIONS OF NEOMYCIN SULPHATE


How Neomycin Sulphate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Neomycin Sulphate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Neomycin Sulphate

No Studies Found