Generic ( Vitamin B12 )


Typical use Of Vitamin B12 :Addisonian Pernicious Anaemia, Congenital Cobalamine Malabsorption, Congenital Intrinsic Factor Deficiency, Homocystenemia, Ileal Resection, Methylmalonylacidurias, Nutrition Deficiency, Post Gastrectomy Vit B-12 Deficiency.
Mechanism of action of Vitamin B12 :Vitamin B12 Is Used In The Body In Two Forms: Methylcobalamin And 5-deoxyadenosyl Cobalamin. The Enzyme Methionine Synthase Needs Methylcobalamin As A Cofactor. This Enzyme Is Involved In The Conversion Of The Amino Acid Homocysteine Into Methionine. Methionine In Turn Is Required For DNA Methylation. 5-Deoxyadenosyl Cobalamin Is A Cofactor Needed By The Enzyme That Converts L-methylmalonyl-CoA To Succinyl-CoA. This Conversion Is An Important Step In The Extraction Of Energy From Proteins And Fats.
Drug Interaction of Vitamin B12 :Cyanocobalamin Is Known To Interact With Other Drugs Like Alcohol, Chloramphenicol, Cholestyramine, Colchicine, Epoetin, Glucose, Neomycin, Omeprazole. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Vitamin B12 :Hypersensitivity Reactions, Shivering, Dyspnea, Persistant Urticaria, Bronchospasm.


INTERACTIONS OF VITAMIN B12


How Vitamin B12 will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Vitamin B12 will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Vitamin B12

No Studies Found