Medicine : Vdruf

Name:Vdruf
Type:Syrup
Manufacturer:Dwd Pharmaceuticals Ltd
Generic Use:Ketoconazole , Zinc
Composition:Ketoconazole(2%W/V) , Zinc(1%W/V)
Substitutes:vdruf , vdruf


Generic ( Ketoconazole )



Typical use Of Ketoconazole :Blastomycosis, Candidiasis, Candiduria, Chromomycosis, Chronic Mucocutaneous Candidiasis, Coccidloidomycosis, Histoplasmosis, Oesophageal Candidiasis, Orophyaryngeal Candidiasis, Paracoccidloidomycosis. Chronic Vag Candidiasis.
Mechanism of action of Ketoconazole :Ketoconazole Interacts With 14-? Demethylase, A Cytochrome P-450 Enzyme Necessary For The Conversion Of Lanosterol To Ergosterol Causes Inhibition Of Ergosterol Synthesis And Increased Fungal Cellular Permeability. Other Mechanisms May Involve The Inhibition Of Endogenous Respiration, Interaction With Membrane Phospholipids, Inhibition Of Yeast Transformation To Mycelial Forms, Inhibition Of Purine Uptake, And Impairment Of Triglyceride And/or Phospholipid Biosynthesis. Ketoconazole Can Also Inhibit The Synthesis Of Thromboxane And Sterols Such As Aldosterone, Cortisol, And Testosterone.
Drug Interaction of Ketoconazole :Ketoconazole Is Known To Interact With Other Drugs Like Abiraterone Acetate, Alcohol, Alfentanil (HCl), Aliskiren, Alprazolam, Aluminium Hydroxide And Oxide, Amphotericin B, Aprepitant, Artesunate, Astemizole, Beclomethasone (Dipropionate), Bosentan, Carbamazepine, Cimetidine (HCl), Cisapride, Corticotropin, Cyclosporin A, Dabigatran, Desonide, Didanosine, Docetaxel, Eplerenone, Erlotinib, Famotidine, Fexofenadine, Flunisolide, Indinavir (Sulphate). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Choice That May Strictly Be Required.
Side effects of Ketoconazole :Impotence, Papilloedema, Androgen Suppression, Oligospermia, Gynecomastia, Dizziness, Headache, Nausea, Vomiting, Alopecia, Diarrhea, Abdominal Pain, Urticaria, Pruritus, Itching, Thrombocytopenia, Photophobia.

INTERACTIONS OF KETOCONAZOLE


How Ketoconazole will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ketoconazole will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ketoconazole

No Studies Found






Generic ( Zinc )



Typical use Of Zinc :Zinc Is Used To Treat Zinc Deficiency, Which May Result In Slow Growth In Infants And Children, Delayed Sexual Development In Adolescents And Impotence In Men; Hair Loss, Diarrhea, Eye And Skin Sores, Loss Of Appetite, Weight Loss, Problems With Wound Healing, Decreased Ability To Taste Food, And Lower Alertness Levels.
Mechanism of action of Zinc :The Exact Mechanism Of Action Is Not Known. However, Zinc Is Important For Immunity Against Infections. Zinc Is Needed For The Proper Growth And Maintenance Of The Human Body. It Helps Speed Recovery From The Common Cold And Reduces Its Symptoms, And Eye Disease That Gradually Causes Vision Loss.
Drug Interaction of Zinc :Zinc May Interact With Drugs Such As Quinolone (ciprofloxacin) Or Tetracycline Antibiotics (tetracycline), Penicillamine (a Drug Used To Treat Rheumatoid Arthritis), And Thiazide Diuretics (such As Chlorthalidone And Hydrochlorothiazide). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Zinc :Taking Too Much Of Zinc Above The Recommended Amounts May Cause Urge To Vomit, Vomiting, Loss Of Appetite, Stomach Cramps, Diarrhea, And Headaches. Prolonged Use Of Too Much Zinc May Cause Low Copper Levels, Lower Immunity, And Low Levels Of HDL Cholesterol (the “good” Cholesterol).

INTERACTIONS OF ZINC


How Zinc will impact on Pregnancy ?

There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Zinc will impact during lactation(breastfeeding) ?

There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Zinc

No Studies Found