Medicine : Vabratz

Name:Vabratz
Type:Tablet
Manufacturer:Intra Labs India Pvt Ltd
Generic Use:Tizanidine , Valdecoxib
Composition:Tizanidine(2mg) , Valdecoxib(20Mg)
Substitutes:vabratz , zulu , vabratz , zulu


Generic ( Tizanidine )



Typical use Of Tizanidine :Cerebral Palsy, Cerebrovascular Accident, Myelopathy, Nausea And Vomiting (acute Attacks), Sclerosis, Spasticity, Spastiicity Associated With Multiple Sclerosis.
Mechanism of action of Tizanidine :Tizanidine Reduces Spasticity By Increasing Presynaptic Inhibition Of Motor Neurons Through Agonist Action At A2-adrenergic Receptor Sites.
Drug Interaction of Tizanidine :Tizanidine Is Known To Interact With Other Drugs Like Alcohol, Diazoxide, Digoxin, Fosphenytoin. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Tizanidine :Dizziness, Drowsiness, Fatigue, Nausea, Insomnia, Dry Mouth, Hallucination, Muscle Weakness, Somnolence, GI Disturbance.

INTERACTIONS OF TIZANIDINE


How Tizanidine will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Tizanidine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Tizanidine

No Studies Found






Generic ( Valdecoxib )



Typical use Of Valdecoxib :Dysmenorrhoea, Muscle Relaxation.
Mechanism of action of Valdecoxib :Both COX-1 And COX-2 Catalyze The Conversion Of Arachidonic Acid To Prostaglandin (PG) H2, The Precursor Of PGs And Thromboxane. Valdecoxib Selectively Inhibits The Cyclooxygenase-2 (COX-2) Enzyme, Important For The Mediation Of Inflammation And Pain.
Drug Interaction of Valdecoxib :Valdecoxib Is Known To Interact With Other Drugs Like Fluconazole, Ketoconazole, Lithium. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Valdecoxib :Palpitation, Dry Mouth, Confusion, Dysphonia, Weight Gain, Cough, Stomatitis, Syncope, Cerebrovascular Disorders, Hypertonia, Intestinal Obstruction, Belching, Taste Disturbance, Hypoesthesia.

INTERACTIONS OF VALDECOXIB


How Valdecoxib will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Valdecoxib will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Valdecoxib

No Studies Found