Medicine : Unifex

Name:Unifex
Type:Tablet
Manufacturer:Bestochem Formulations India Ltd
Generic Use:Cephalexin , Probenecid
Composition:Cephalexin(250Mg) , Probenecid(250Mg)
Substitutes:unifex , unifex sule , unifex , unifex sule


Generic ( Cephalexin )



Typical use Of Cephalexin :Bone And Joint Infection, Dental Infections, Genitourinary Tract Infections, Otitis Media, Respiratory Tract Infections, Schizophrenia And Other Psychoses, Skin Infections.
Mechanism of action of Cephalexin :Cephalexin Binds To Specific Penicillin-binding Proteins (PBPs) Located Inside The Bacterial Cell Wall, It Inhibits The Third And Last Stage Of Bacterial Cell Wall Synthesis. Cell Lysis Is Then Mediated By Bacterial Cell Wall Autolytic Enzymes Such As Autolysins.
Drug Interaction of Cephalexin :Cephalexin Is Known To Interact With Other Drugs Like Pivmecillinam (HCl), Probenecid, Protamine (Sulphate), Reviparin Sodium, Streptomycin. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That Maystrictly Be Required.
Side effects of Cephalexin :Hypersensitivity Reactions, Interstitial Nephritis, Vulvo Vaginitis, Dizziness, Headache, Nausea, Vomiting, Diarrhea, Skin Reactions, Vaginitis, Genital Moniliasis, Vaginal Discharge, Neutropenia, GI Disturbance.

INTERACTIONS OF CEPHALEXIN


How Cephalexin will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Cephalexin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Cephalexin

No Studies Found






Generic ( Probenecid )



Typical use Of Probenecid :Chronic Gout And Hyperuricaemia, To Prolong Penicillin Or Ampicillin Action By Enhancing And Sustaining Their Blood Levels.
Mechanism of action of Probenecid :Probenecid Increases Excretion Of Uric Acid By Competitively Blocking Its Reabsorption At The Proximal Convoluted Tubule Thus Lowering Serum Uric Acid Levels And Eventually Reducing Urate Deposits In The Tissues. It Also Causes Plasma Levels Of Weak Organic Acids (eg, Penicillins And Most Cephalosporins) To Increase By Competitively Inhibiting Their Renal Tubular Secretion.
Drug Interaction of Probenecid :Probenecid Blocks Excretion Of Some Drugs By The Kidney And, Therefore, May Increase Blood Levels And Side Effects Of Methotrexate (Rheumatrex, Trexall) And Nonsteroidal Antiinflammatory Drugs (Nsaids), For Example, Ibuprofen (Advil), Naproxen (Aleve), Indomethacin (Indocin), Ketorolac (Toradol) And Others. Aspirin May Reduce The Action Of Probenecid Through Unknown Mechanisms.
Side effects of Probenecid :Seizures (overdosage), Headache, Anorexia.

INTERACTIONS OF PROBENECID


How Probenecid will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Probenecid will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Probenecid

No Studies Found