Medicine : Tussnil (100ml)

Name:Tussnil (100ml)
Type:Syrup
Manufacturer:Pfizer Limited
Generic Use:Bromhexine , Chlorphenamine , Dextromethorphan , Menthol
Composition:Bromhexine(4 Mg) , Chlorphenamine(2 Mg) , Dextromethorphan(5 Mg) , Menthol(#N/A)
Substitutes:tussnil (100ml) , tussnil (100ml) , tussnil (100ml) , tussnil (100ml)


Generic ( Bromhexine )


Typical use Of Bromhexine :To Clear Mucus From The Respiratory Tract And Mainly Used In Acute And Chronic Respiratory Diseases Such As Bronchitis (inflammation Of Lungs) And Sinusitis (inflammation Of Sinuses).
Mechanism of action of Bromhexine :Bromhexine Works By Thinning The Mucus In The Airways, Thus Making The Mucus Less Sticky And Facilitating The Removal Of The Mucus.
Drug Interaction of Bromhexine :No Clinically Relevant Unfavorable Interactions With Other Medications Have Been Reported. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Bromhexine :May Cause Gastric Disturbances Such As Diarrhea, Urge To Vomit (nausea), Vomiting, Indigestion, Bloating And Other Mild Stomach Side Effects, Dizziness, Headache, Sweating And Skin Rashes.

INTERACTIONS OF BROMHEXINE

How Bromhexine will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Bromhexine will impact during lactation(breastfeeding) ?

Safest: Evidence From Clinical Studies Has Shown That This Drug When Taken By Breastfeeding Mothers Has Not Shown Any Major Side Effects In Infants. The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare Or The Drug Does Not Reach The Infant Through Breast Milk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Bromhexine

No Studies Found





Generic ( Chlorphenamine )


Typical use Of Chlorphenamine :Allergic Conditions. Adjunct In The Emergency Treatment Of Anaphylactic Shock.
Mechanism of action of Chlorphenamine :Chlorphenamine Is An H1-receptor Antagonist Which Competetively Blocks H1-receptor Sites On Tissues.
Drug Interaction of Chlorphenamine : Potentiates Sedative Effect Of Psychotropic Drugs E.g. Barbiturates, Hypnotics, Opioid Analgesics, Anxiolytics And Antipsychotics. Interaction With Alcohol Could Be Dangerous (sedation/excitation).
Side effects of Chlorphenamine :CNS Depression, Sedation, Drowsiness, Lassitude, Dizziness. GI Upsets, Anorexia, Or Increased Appetite, Epigastric Pain, Blurring Of Vision, Dysuria, Dryness Of Mouth, Tightness In Chest, Hypotension, Muscular Weakness, Tinnitus, Euphoria, Headache, Paradoxical CNS Stimulation. CV Collapse And Respiratory Failure.

INTERACTIONS OF CHLORPHENAMINE

How Chlorphenamine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Chlorphenamine will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Chlorphenamine

No Studies Found





Generic ( Dextromethorphan )


Typical use Of Dextromethorphan :To Relieve Dry Coughs (coughs That Do Not Produce Phlegm Or Mucus On The Chest).
Mechanism of action of Dextromethorphan :Dextromethorphan Acts On The Brain And Increases The Threshold For Coughing Or Suppresses Coughing.
Drug Interaction of Dextromethorphan :Other Cough And Cold Medicine, Alcohol Or Other CNS Depressants Such As Monoamine Oxidase Inhibitors, Other Medicines For Mental Health Conditions, And Medicines For Heart Problems Such As Amiodarone, Haloperidol, Propafenone, Quinidine, SRRIs, And Thioridazine Should Not Be Taken Along With Dextromethorphan. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Dextromethorphan :Skin Rash, Urge To Vomit, Being Sick, Diarrhea, Drowsiness, Dizziness, Feeling Of Excitation Or Confusion, Difficulty Breathing.

INTERACTIONS OF DEXTROMETHORPHAN

How Dextromethorphan will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Dextromethorphan will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Dextromethorphan

No Studies Found





Generic ( Menthol )


Typical use Of Menthol :Pharmaceutical Aid
Mechanism of action of Menthol :Menthol Primarily Activates The Cold-sensitive TRPM8 Receptors In The Skin. Menthol, After Topical Application, Causes A Feeling Of Coolness Due To Stimulation Of 'cold' Receptors By Inhibiting Ca++ Currents Of Neuronal Membranes. It May Also Yield Analgesic Properties Via Kappa-opioid Receptor Agonism.
Drug Interaction of Menthol :Menthol Is Known To Interact With Other Drugs Like Alcohol. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Menthol :Nystagmus, Contact Dermatitis, Apnea. Menthol Produces Potentially Life-threatening Effects Which Include Coma. Overdosage Of Menthol Include Irregularities In Heart Rhythm. The Symtomatic Adverse Effects Produced By Menthol Such As Vertigo, Drowsiness, Ataxia, Abdominal Pain, Nausea And Vomiting.

INTERACTIONS OF MENTHOL

How Menthol will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Menthol will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Menthol

No Studies Found