Medicine : Tretinc

Generic Use:Clindamycin , Tretinoin
Composition:Clindamycin(1%W/W) , Tretinoin(0.025%w/w)
Substitutes:retino ac gel(15gm) , tretinc , retino ac gel(15gm) , tretinc

Generic ( Clindamycin )

Typical use Of Clindamycin :Acne Vulgaris, Babesiosis, Bacterial Infections, Bacterial Vaginosis, Dental Infections, Endocarditis, Hidradenitis Suppurativa, Intra-abdominal Infections, Malaria, Osteomyelitis, Pelvic Infections, Peritonitis, Pulmonary Infection, Septic Arthritis, Septicaemia.
Mechanism of action of Clindamycin :Systemic/vaginal Clindamycin Inhibits Protein Synthesis Of Bacteria By Binding To The 50S Ribosomal Subunits Of The Bacteria. Specifically, It Binds Primarily To The 23s RNA Subunit. Topical Clindamycin Reduces Free Fatty Acid Concentrations On The Skin And Suppresses The Growth Of Propionibacterium Acnes (Corynebacterium Acnes) , An Anaerobe Found In Sebaceous Glands And Follicles.
Drug Interaction of Clindamycin :Clindamycin Is Known To Interact With Other Drugs Like Bamifylline, Calcium Gluconate, Distigmine (Br), Gentamicin, Lincomycin (HCl), Pancuronium (Br), Physostigmine, Rivastigmine, Rocuronium (Br), Sodium Thiosulphate.
Side effects of Clindamycin :Elevated SGPT & SGOT, Elevated Alkaline Phosphatase Concentration, Esophageal Ulceration, Pseudomembranous Colitis, Cardiac Arrest, Colonic Ulceration, Nausea, Vomiting, Abdominal Pain, Rashes, Vaginitis, Contact Dermatitis.


How Clindamycin will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Clindamycin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Clindamycin

No Studies Found

Generic ( Tretinoin )

Typical use Of Tretinoin :Acne Vulgaris, Promyelocytic Leukemia.
Mechanism of action of Tretinoin :Tretinoin Stimulates Mitosis And Turnover Of Follicular Epithelial Cells And Reduce Their Cohesiveness. This Facilitates Extrusion Of Existing Comedones And Prevents Formation Of New Comedone. It Also Exhibits Thinning Effect On The Stratum Corneum. In Acute Promyelocytic Leukaemia, It Induces Cellular Differentiation And Decreases Proliferations.
Drug Interaction of Tretinoin :Tretinoin Is Known To Interact With Other Drugs Like Alcohol, Benzoyl Peroxide, Minoxidil, Resorcinol, Retinol (Vitamin A), Salicylic Acid, Sulphur. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Tretinoin :Erythema, Irritation, Warmth Feeling.


How Tretinoin will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Tretinoin will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Tretinoin

No Studies Found