Medicine : Topex Expe(100ml)

Name:Topex Expe(100ml)
Type:Syrup
Manufacturer:Ozone Pharmaceuticals Ltd
Generic Use:Diphenhydramine Hydrochloride , Ammonium Chloride , Sodium Citrate , Menthol
Composition:Diphenhydramine Hydrochloride(15 Mg/10ml) , Ammonium Chloride(150 Mg/10ml) , Sodium Citrate(85 Mg/10ml) , Menthol(2.5 Mg/10ml)
Substitutes:topex expe(100ml) , topex expe(100ml) , topex expe(100ml) , topex expe(100ml)


Generic ( Diphenhydramine Hydrochloride )



Typical use Of Diphenhydramine Hydrochloride :Anaphylactic Reactions, Angioneurotic Edema, Menieres Disease, Motion Sickness, Parkinsonism, Perennial Rhinitis, Pruritus, Seasonal Rhinitis.
Mechanism of action of Diphenhydramine Hydrochloride :Diphenhydramine Competes With Free Histamine For Binding At HA-receptor Sites. This Antagonizes The Effects Of Histamine On HA-receptors, Leading To A Reduction Of The Negative Symptoms Brought On By Histamine HA-receptor Binding.
Drug Interaction of Diphenhydramine Hydrochloride :Diphenhydramine Is Known To Interact With Other Drugs Like Alcohol, Amphotericin B, Atomoxetine HCl, Atropine (Sulphate), Nabilone, Oxymorphone, Pericyazine, Rizatriptan. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Diphenhydramine Hydrochloride :Flushing, Nausea, Tachycardia, Convulsions, Coma, Drowsiness, Dry Mouth, Urinary Retention, Hallucinations, Dizziness, Tiredness, Ataxia, Tremors, Nervousness, Tinnitus, Blurred Vision, Sedation, Diplopia, Euphoria.

INTERACTIONS OF DIPHENHYDRAMINE HYDROCHLORIDE


How Diphenhydramine Hydrochloride will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Diphenhydramine Hydrochloride will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Diphenhydramine Hydrochloride

No Studies Found






Generic ( Ammonium Chloride )



Typical use Of Ammonium Chloride :Cough, Metabolic Alkalosis, Urinary Retention.
Mechanism of action of Ammonium Chloride :The Therapeutic Effects Of Ammonium Chloride Depend Upon The Ability Of The Kidney To Utilize Ammonia In The Excretion Of An Excess Of Fixed Anions And The Conversion Of Ammonia To Urea By The Liver, Thereby Liberating Hydrogen (H+) And Chloride (Cl?) Ions Into The Extracellular Fluid.
Drug Interaction of Ammonium Chloride :Ammonium Chloride Is Known To Interact With Other Drugs Like Methadone. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ammonium Chloride :Encephalopathy, Pain, Nausea And Vomiting, Hypokalemia.

INTERACTIONS OF AMMONIUM CHLORIDE


How Ammonium Chloride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ammonium Chloride will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ammonium Chloride

No Studies Found






Generic ( Sodium Citrate )



Typical use Of Sodium Citrate :Information Not Available.
Mechanism of action of Sodium Citrate :Sodium Citrate Is Used To Treat A Number Of Problems. It Is An Osmotic Laxative, Which Induces A Laxative Effect (stimulating Stool Production). It Is Used To Relieve Constipation And Works (when Used As An Enemal For Rectal Use) By Causing Water To Be Drawn Into The Lower Bowel (colon) To Increase The Water Content And Volume Of Stools, Making Them Softer And Easier To Pass, Relieving Constipation. It Also Used For Other Purposes When Taken By Mouth, Such As In Adult Women For The Relief Of Symptoms Due To Cystitis (inflammation Of The Bladder Owing To An Infection Of Urine In Women) Where It Reduces The Acidity Of Urine, And Before General Anaesthesia To Prevent Stomach Acid Aspiration (inhalation Of Stomach Acid Into The Airways), Which May Happen During A Surgical Operation Or In Pregnant Women During Child Birth. In General, This Drug Is Used To Relieve Constipation, Treat Symptoms Of Mild Cystitis Or To Prevent Stomach Acid Aspiration During Anaesthesia. Benefits Of Being On This Drug Can Include Regular Bowel Movements, Relief From The Painful Symptoms Of Cystisis And Problems Occurring After Inhalation Of Acid Stomach Contents During Surgery.
Drug Interaction of Sodium Citrate :Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Sodium Citrate :Nausea, Stomach Upset, Skin Rash, Acute Toxicity.

INTERACTIONS OF SODIUM CITRATE


How Sodium Citrate will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Sodium Citrate will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Sodium Citrate

No Studies Found






Generic ( Menthol )



Typical use Of Menthol :Pharmaceutical Aid
Mechanism of action of Menthol :Menthol Primarily Activates The Cold-sensitive TRPM8 Receptors In The Skin. Menthol, After Topical Application, Causes A Feeling Of Coolness Due To Stimulation Of 'cold' Receptors By Inhibiting Ca++ Currents Of Neuronal Membranes. It May Also Yield Analgesic Properties Via Kappa-opioid Receptor Agonism.
Drug Interaction of Menthol :Menthol Is Known To Interact With Other Drugs Like Alcohol. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Menthol :Nystagmus, Contact Dermatitis, Apnea. Menthol Produces Potentially Life-threatening Effects Which Include Coma. Overdosage Of Menthol Include Irregularities In Heart Rhythm. The Symtomatic Adverse Effects Produced By Menthol Such As Vertigo, Drowsiness, Ataxia, Abdominal Pain, Nausea And Vomiting.

INTERACTIONS OF MENTHOL


How Menthol will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Menthol will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Menthol

No Studies Found