Medicine : Toff Plus

Name:Toff Plus
Type:Syrup
Manufacturer:Panacea Biotec Ltd
Generic Use:Chlorpheniramine , Dextromethorphan , Phenylpropanolamine
Composition:Chlorpheniramine(2mg) , Dextromethorphan(15Mg) , Phenylpropanolamine(12.5Mg)
Substitutes:toff plus , toff plus , toff plus


Generic ( Chlorpheniramine )


Typical use Of Chlorpheniramine :Chlorpheniramine Is Used To Treat Symptoms Of Allergic Conditions Such As Runny Nose, Itchy Skin Rash With Irregular Raised Patches (hives), Red And Swollen Airways, Common Cold, And Hay Fever, Food Allergy, Reaction To Drugs Or Vaccines, And In Insect Bites.
Mechanism of action of Chlorpheniramine :Chlorpheniramine Reduces Allergy Symptoms By Blocking The Activity Of A Natural Bodily Substance (histamine) That Is Produced During Allergic Reactions. It Also Blocks The Activity Of Another Substance (acetylcholine) That Further Helps Dry Up Certain Body Fluids To Cause Relief From Runny Nose.
Drug Interaction of Chlorpheniramine :Chlorpheniramine Interacts With Diazepam, Nitrazepam, Phenelzine, Tranylcypromine Or Anti-depressants To Cause Effects Like Blurred Vision And Dry Mouth. Chlorpheniramine Enhances The Effect Of Phenytoin And May Cause Toxic Reaction. Avoid Excessive Alcohol Consumption. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Chlorpheniramine :Common Side-effects Include Sleepiness And Difficulty In Remaining Alert, Unusual Tiredness Or Weakness, Headache, Dizziness, Slowing Of Physical And Emotional Reactions, Dry Mouth, Blurred Vision, Dry Eyes, Sensitivity To Sunlight Or Artificial Light, Diarrhea, Urge To Vomit, Vomiting, And Skin Reactions.

INTERACTIONS OF CHLORPHENIRAMINE

How Chlorpheniramine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Chlorpheniramine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Chlorpheniramine

No Studies Found





Generic ( Dextromethorphan )


Typical use Of Dextromethorphan :To Relieve Dry Coughs (coughs That Do Not Produce Phlegm Or Mucus On The Chest).
Mechanism of action of Dextromethorphan :Dextromethorphan Acts On The Brain And Increases The Threshold For Coughing Or Suppresses Coughing.
Drug Interaction of Dextromethorphan :Other Cough And Cold Medicine, Alcohol Or Other CNS Depressants Such As Monoamine Oxidase Inhibitors, Other Medicines For Mental Health Conditions, And Medicines For Heart Problems Such As Amiodarone, Haloperidol, Propafenone, Quinidine, SRRIs, And Thioridazine Should Not Be Taken Along With Dextromethorphan. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Dextromethorphan :Skin Rash, Urge To Vomit, Being Sick, Diarrhea, Drowsiness, Dizziness, Feeling Of Excitation Or Confusion, Difficulty Breathing.

INTERACTIONS OF DEXTROMETHORPHAN

How Dextromethorphan will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Dextromethorphan will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Dextromethorphan

No Studies Found





Generic ( Phenylpropanolamine )


Typical use Of Phenylpropanolamine :Appetite Suppresser, Cold, Congestion, Cough, Urinary Incontinence.
Mechanism of action of Phenylpropanolamine :Phenylpropanolamine Acts Directly On Alpha- And, To A Lesser Degree, Beta-adrenergic Receptors In The Mucosa Of The Respiratory Tract. Stimulation Of Alpha-adrenergic Receptors Produces Vasoconstriction, Reduces Tissue Hyperemia, Edema, And Nasal Congestion, And Increases Nasal Airway Patency. PPA Indirectly Stimulates Beta-receptors, Producing Tachycardia And A Positive Inotropic Effect.
Drug Interaction of Phenylpropanolamine :Phenylpropanolamine (HCl) Is Known To Interact With Other Drugs Like Acebutolol, Atropine (Sulphate), Bromocriptine (Mesylate), Debrisoquine (Sulphate), Doxepin (HCl), Ephedrine, Furazolidone, Guanethidine, Indomethacin, Moclobemide, Sibutramine, Thioridazine (HCl). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Phenylpropanolamine :Hypertension, Epileptic Seizures, Hallucinations, Psychosis, Dizziness, Headache, Nausea, Palpitation, Tremors, Chest Tightness.

INTERACTIONS OF PHENYLPROPANOLAMINE

How Phenylpropanolamine will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Phenylpropanolamine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Phenylpropanolamine

No Studies Found