Medicine : Thromboflux

Name:Thromboflux
Type:Injection
Manufacturer:Bharat Serums & Vaccines Ltd
Generic Use:Streptokinase
Composition:Streptokinase(1500000 Iu)
Substitutes:thromboflux , stpase (1500000iu)


Generic ( Streptokinase )



Typical use Of Streptokinase :Acute Myocardial Infarction, Arterial Thrombosis, Deep Vein Thrombosis, Desloughing Wounds, Duodenal Ulcer And Gastric Ulcer, Myocardial Infarction, Prophylaxis Of NSAID-associated Gastric Or Duodenal Ulcer, Pulmonary Embolism, Thrombosis.
Mechanism of action of Streptokinase :Plasminogen Is An Inactive Molecule That Becomes Activated To Plasmin When The Arg/Val Bond Is Cleaved. Plasmin Breaks Down Fibrin Clots Created By The Blood Clotting Cascade. Streptokinase Forms A Highly Specific 1:1 Enzymatic Complex With Plasminogen Which Converts Inactive Plasminogen Molecules Into Active Plasmin. Plasmin Degrades Fibrin Clots As Well As Fibrinogen And Other Plasma Proteins. This In Turn Leads To The Degradation Of Blood Clots.
Drug Interaction of Streptokinase :Antagonistic Effects With Antifibrinolytic Agents E.g. Aminocaproic Acid.
Side effects of Streptokinase :Fever, Chills, Nausea And Vomiting, Rigors.

INTERACTIONS OF STREPTOKINASE


How Streptokinase will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Streptokinase will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Streptokinase

No Studies Found