Medicine : Terlins (1mg/10mg)

Name:Terlins (1mg/10mg)
Manufacturer:Neiss Labs Pvt Ltd
Generic Use:Terlipressin
Substitutes:terlins (1mg/10mg)

Generic ( Terlipressin )

Typical use Of Terlipressin :Bleeding From Oesophageal Varices.
Mechanism of action of Terlipressin :Terlipressin Acts On Three Different Receptors, Vasopressin Receptor V1a (which Initiates Vasoconstriction, Liver Gluconeogenesis, Platelet Aggregation And Release Of Factor VIII), Vasopressin Receptor V1b (which Mediates Corticotrophin Secretion From The Pituitary) And Vasopressin Receptor V2 Which Controls Free Water Reabsorption In The Renal Medullar. The Binding Of Terlipressin To The V2 Receptor Activates Adenylate Cyclase Which Causes The Release Of Aquaporin 2 Channels Into The Cells Lining The Renal Medullar Duct. This Allows Water To Be Reabsorbed Down An Osmotic Gradient So The Urine Is More Concentrated.
Drug Interaction of Terlipressin :Terlipressin Is Known To Interact With Other Drugs Like Noradrenaline (Acid Tartrate). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Terlipressin :Cardiac Arrhythmias, Angina, Abdominal Cramps, Headache, Nausea, Abdominal Cramps, Weakness Of The Leg, Skin Pallor.


How Terlipressin will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Terlipressin will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Terlipressin

No Studies Found