Medicine : Tenovate Skin(15gm)

Name:Tenovate Skin(15gm)
Type:Cream
Manufacturer:Glaxo Smithkline Pharmaceuticals Ltd (allenburys)
Generic Use:Clobetasol , Clobetasone
Composition:Clobetasol(0.05%v /v) , Clobetasone(0.05% W/w)
Substitutes:tenovate skin(15gm) , tenovate skin(15gm)


Generic ( Clobetasol )



Typical use Of Clobetasol :To Treat Itching, Redness, Dryness, Inflammation, And Discomfort Of Various Scalp And Skin Conditions, Including Psoriasis (immune-mediated Skin Disease With Red Scaly Patches) And Eczematous Dermatitis.
Mechanism of action of Clobetasol :Clobetasol Is A Highly Active Corticosteroid With Topical Anti-inflammatory Activity. It Reduces Inflammation By Vasoconstriction And Decrease In Collagen Synthesis. When Clobetasol Is Applied To The Skin It Works By Acting Inside The Skin Cells To Decrease The Release Of These Inflammatory Substances. This Reduces Swelling, Redness And Itch.
Drug Interaction of Clobetasol :Clobestol May Interact With Prednisone And Cyclosporine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Clobetasol :Severe Irritation Of Treated Skin, Soreness Around The Mouth, Burning, Dryness, Irritation, Itching, Or Redness Of Skin (usually Mild And Temporary), Eye Pain (if Certain Products Have Been Used Near The Eye), Headache, Increased Redness Or Scaling Of Skin Sores (usually Mild And Temporary), Changes In Skin Color, Skin Infection, Skin Rash (usually Mild And Temporary), Softening And Tearing Of The Skin And Thinning Of The Skin With Easy Bruising.

INTERACTIONS OF CLOBETASOL


How Clobetasol will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Clobetasol will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Clobetasol

No Studies Found






Generic ( Clobetasone )



Typical use Of Clobetasone : Dermatitis, Eczema, Herpes Simplex Infections, Inflammatory Eye Disease, Psoriasis.
Mechanism of action of Clobetasone :Clobetasone Diffuse Across Cell Membranes And Complex With Specific Cytoplasmic Receptors. These Complexes Then Enter The Cell Nucleus, Bind To DNA (chromatin), And Stimulate Transcription Of Messenger RNA (mRNA) And Subsequent Protein Synthesis Of Various Inhibitory Enzymes Responsible For The Anti-inflammatory Effects Of Topical Corticosteroids. These Anti-inflammatory Effects Include Inhibition Of Early Processes Such As Edema, Fibrin Deposition, Capillary Dilatation, Movement Of Phagocytes Into The Area, And Phagocytic Activities. Later Processes, Such As Capillary Production, Collagen Deposition, And Keloid Formation Also Are Inhibited By Corticosteroids.The Overall Actions Of Topical Corticosteroids Are Catabolic.
Drug Interaction of Clobetasone :Clobetasone Is Known To Interact With Other Drugs Like Live Vaccines, Barbiturates, Carbamazepine, Phenytoin, Primidone Or Rifampicin, Thiazide Or Furosemide, NSAIDs, Anticoagulants, Salicylates, Antimuscarinics.
Side effects of Clobetasone :Telangiectasia, Striae, Minor Atrophic Changes, Epidermis Atrophy, Dermal Collagen Atrophy, Perioral Dermatitis, Skin Ulceration, Allergy, Glaucoma, Cataract.

INTERACTIONS OF CLOBETASONE


How Clobetasone will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Clobetasone will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Clobetasone

No Studies Found