Medicine : Synclar (500mg)

Name:Synclar (500mg)
Manufacturer:Cipla Ltd
Generic Use:Clarithromycin
Composition:Clarithromycin(500 Mg)
Substitutes:clarimin (500mg) , larit (500mg) , clarivir (500mg) , f clar(500mg) , t clar(500mg) , monoclar (500mg) , bioclar (500mg) , claricin (500mg) , clarbact (500mg) , clarithro (500mg) , broclars (500mg) , clarithro xr(500mg) , crixan er(500mg) , neklitro (500mg) , urclar sr(500mg) , clariwin (500mg) , anaclar (500mg) , clarics (500mg) , urclar od(500mg) , clarie od(500mg) , klarim (500mg) , macroclar (500mg) , crixan (500mg) , maclar sr(500mg) , crixan od(500mg) , maclar (500mg) , heliclar (500mg) , celex (500mg) , claribid od(500mg) , claribid fc(500mg) , claribid (500mg) , klacid (500mg) , celex od(500mg) , clarimac (500mg) , synclar (500mg) , clarwin (500mg) , klacid i.v(500mg) , truclar (500tab)

Generic ( Clarithromycin )

Typical use Of Clarithromycin :URTI, Pharyngitis And Sinusitis, LRTI, Bronchitis And Pneumonia, Skin And Soft Tissue Infection. H.Pylori Infection.Infection Due To Mycobacterium Avium Complex (MAC).
Mechanism of action of Clarithromycin :Clarithromycin Is First Metabolized To 14-OH Clarithromycin, Which Is Active And Works Synergistically With Its Parent Compound. Like Other Macrolides, It Then Penetrates Bacteria Cell Wall And Reversibly Binds To Domain V Of The 23S Ribosomal RNA Of The 50S Subunit Of The Bacterial Ribosome, Blocking Translocation Of Aminoacyl Transfer-RNA And Polypeptide Synthesis. Clarithromycin Also Inhibits The Hepatic Microsomal CYP3A4 Isoenzyme And P-glycoprotein, An Energy-dependent Drug Efflux Pump.
Drug Interaction of Clarithromycin :Clarithromycin Is Known To Interact With Other Drugs Like Alprazolam, Artesunate, Astemizole, Carbamazepine, Cimetidine (HCl), Cisapride, Cyclosporin A, Digoxin, Dihydroergotamine (Mesylate), Disopyramide, Ergotamine (Tartrate), Erlotinib, Fluoxetine (HCl), Isosorbide (Dinitrate), Loratadine, Lorazepam, Lovastatin.
Side effects of Clarithromycin :Pseudomembranous Colitis, Renal Failure, Interstitial Nephritis, Headache, Nausea, Vomiting, Diarrhea, Abdominal Pain, Phlebitis, Glossitis, Stomatitis.


How Clarithromycin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Clarithromycin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Clarithromycin

No Studies Found