Medicine : Symine Exp(100ml)

Name:Symine Exp(100ml)
Type:Syrup
Manufacturer:Pfizer Limited
Generic Use:Ammonium Chloride , Bromhexine , Menthol , Pseudoephedrine Hydrochloride
Composition:Ammonium Chloride(50 Mg) , Bromhexine(4 Mg) , Menthol(2.5mg /5ml) , Pseudoephedrine Hydrochloride(30 Mg)
Substitutes:symine exp(100ml) , symine exp(100ml) , symine exp(100ml) , symine exp(100ml)


Generic ( Ammonium Chloride )


Typical use Of Ammonium Chloride :Cough, Metabolic Alkalosis, Urinary Retention.
Mechanism of action of Ammonium Chloride :The Therapeutic Effects Of Ammonium Chloride Depend Upon The Ability Of The Kidney To Utilize Ammonia In The Excretion Of An Excess Of Fixed Anions And The Conversion Of Ammonia To Urea By The Liver, Thereby Liberating Hydrogen (H+) And Chloride (Cl?) Ions Into The Extracellular Fluid.
Drug Interaction of Ammonium Chloride :Ammonium Chloride Is Known To Interact With Other Drugs Like Methadone. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ammonium Chloride :Encephalopathy, Pain, Nausea And Vomiting, Hypokalemia.

INTERACTIONS OF AMMONIUM CHLORIDE

How Ammonium Chloride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ammonium Chloride will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ammonium Chloride

No Studies Found





Generic ( Bromhexine )


Typical use Of Bromhexine :To Clear Mucus From The Respiratory Tract And Mainly Used In Acute And Chronic Respiratory Diseases Such As Bronchitis (inflammation Of Lungs) And Sinusitis (inflammation Of Sinuses).
Mechanism of action of Bromhexine :Bromhexine Works By Thinning The Mucus In The Airways, Thus Making The Mucus Less Sticky And Facilitating The Removal Of The Mucus.
Drug Interaction of Bromhexine :No Clinically Relevant Unfavorable Interactions With Other Medications Have Been Reported. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Bromhexine :May Cause Gastric Disturbances Such As Diarrhea, Urge To Vomit (nausea), Vomiting, Indigestion, Bloating And Other Mild Stomach Side Effects, Dizziness, Headache, Sweating And Skin Rashes.

INTERACTIONS OF BROMHEXINE

How Bromhexine will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Bromhexine will impact during lactation(breastfeeding) ?

Safest: Evidence From Clinical Studies Has Shown That This Drug When Taken By Breastfeeding Mothers Has Not Shown Any Major Side Effects In Infants. The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare Or The Drug Does Not Reach The Infant Through Breast Milk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Bromhexine

No Studies Found





Generic ( Menthol )


Typical use Of Menthol :Pharmaceutical Aid
Mechanism of action of Menthol :Menthol Primarily Activates The Cold-sensitive TRPM8 Receptors In The Skin. Menthol, After Topical Application, Causes A Feeling Of Coolness Due To Stimulation Of 'cold' Receptors By Inhibiting Ca++ Currents Of Neuronal Membranes. It May Also Yield Analgesic Properties Via Kappa-opioid Receptor Agonism.
Drug Interaction of Menthol :Menthol Is Known To Interact With Other Drugs Like Alcohol. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Menthol :Nystagmus, Contact Dermatitis, Apnea. Menthol Produces Potentially Life-threatening Effects Which Include Coma. Overdosage Of Menthol Include Irregularities In Heart Rhythm. The Symtomatic Adverse Effects Produced By Menthol Such As Vertigo, Drowsiness, Ataxia, Abdominal Pain, Nausea And Vomiting.

INTERACTIONS OF MENTHOL

How Menthol will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Menthol will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Menthol

No Studies Found





Generic ( Pseudoephedrine Hydrochloride )


Typical use Of Pseudoephedrine Hydrochloride :Bronchospasm, Nasal Congestion, Rhinitis, Upper Respiratory Tract Infections.
Mechanism of action of Pseudoephedrine Hydrochloride :Pseudoephedrine Is Both An ?-and ?-adrenergic Receptor Agonist. It Causes Vasoconstriction Via Direct Stimulation Of ?-adrenergic Receptors Of The Respiratory Mucosa. It Also Directly Stimulates ?-adrenergic Receptors Causing Bronchial Relaxation, Increased Heart Rate And Contractility.
Drug Interaction of Pseudoephedrine Hydrochloride :Increased Risk Of Hypertension And Arrhythmias If Given With Cardiac Glycosides, Quinidine Or TCAs
Side effects of Pseudoephedrine Hydrochloride :Drowsiness, Anorexia, Anxiety, Restlessness, Insomnia, Sleep DisturbancesX, Dry Mouth, Tremor.

INTERACTIONS OF PSEUDOEPHEDRINE HYDROCHLORIDE

How Pseudoephedrine Hydrochloride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Pseudoephedrine Hydrochloride will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Pseudoephedrine Hydrochloride

No Studies Found