Medicine : Sonaderm Nm Cr(15gm)

Name:Sonaderm Nm Cr(15gm)
Type:Cream
Manufacturer:Blue Cross Laboratories Ltd
Generic Use:Clobetasol , Miconazole , Neomycin
Composition:Clobetasol(0.05%w /w) , Miconazole(2%w /w) , Neomycin(0.5%w /w)
Substitutes:sonaderm nm cr(15gm) , sonaderm nm cr(15gm) , sonaderm nm cr(15gm)


Generic ( Clobetasol )



Typical use Of Clobetasol :To Treat Itching, Redness, Dryness, Inflammation, And Discomfort Of Various Scalp And Skin Conditions, Including Psoriasis (immune-mediated Skin Disease With Red Scaly Patches) And Eczematous Dermatitis.
Mechanism of action of Clobetasol :Clobetasol Is A Highly Active Corticosteroid With Topical Anti-inflammatory Activity. It Reduces Inflammation By Vasoconstriction And Decrease In Collagen Synthesis. When Clobetasol Is Applied To The Skin It Works By Acting Inside The Skin Cells To Decrease The Release Of These Inflammatory Substances. This Reduces Swelling, Redness And Itch.
Drug Interaction of Clobetasol :Clobestol May Interact With Prednisone And Cyclosporine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Clobetasol :Severe Irritation Of Treated Skin, Soreness Around The Mouth, Burning, Dryness, Irritation, Itching, Or Redness Of Skin (usually Mild And Temporary), Eye Pain (if Certain Products Have Been Used Near The Eye), Headache, Increased Redness Or Scaling Of Skin Sores (usually Mild And Temporary), Changes In Skin Color, Skin Infection, Skin Rash (usually Mild And Temporary), Softening And Tearing Of The Skin And Thinning Of The Skin With Easy Bruising.

INTERACTIONS OF CLOBETASOL


How Clobetasol will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Clobetasol will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Clobetasol

No Studies Found






Generic ( Miconazole )



Typical use Of Miconazole :Vulvo-vaginal Candidiasis, Balanitis.Tinea Vapitis, T Corporis, T Manuum, T Pedis (atheletes Foot), T Barbae, T Cruris, T Unguium Or Onychomycosis, Pityriasis Versicolor.Candidiasis Of Skin And Nails.
Mechanism of action of Miconazole :Miconazole Interacts With 14-? Demethylase, A Cytochrome P-450 Enzyme Necessary To Convert Lanosterol To Ergosterol, Causes Inhibition Of Ergosterol Synthesis Results In Increased Cellular Permeability Causing Leakage Of Cellular Contents. Miconazole May Also Inhibit Endogenous Respiration, Interact With Membrane Phospholipids, Inhibit The Transformation Of Yeasts To Mycelial Forms, Inhibit Purine Uptake, And Impair Triglyceride And/or Phospholipid Biosynthesis.
Drug Interaction of Miconazole :Miconazole (Nitrate) Is Known To Interact With Other Drugs Like Alprazolam, Amphotericin B,astemizole, Carbamazepine, Cisapride, Fosphenytoin, Phenytoin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Miconazole :Cardiac Arrhythmias, Phlebitis, Pruritis, Arachnoiditis, Cardiac Arrest, Anaphylaxis, Drowsiness, Anorexia, Rashes, GI Upset, Flushing, Nausea And Vomiting

INTERACTIONS OF MICONAZOLE


How Miconazole will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Miconazole will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Miconazole

No Studies Found






Generic ( Neomycin )



Typical use Of Neomycin :To Prevent Or Treat Bacterial Diarrhea And Dysentery. It Is Also Used For Pre-operative Sterilization Of The Bowel And To Reduce Symptoms Of Coma Due To Liver Disease (hepatic Coma); To Cure Infected Wound, Ulcers, Burn, External Ear Infections And Conjunctivitis.
Mechanism of action of Neomycin :Neomycin Prevents The Bacterial Growth By Inhibiting The Synthesis Of Protein In Susceptible Bacterial Cells.
Drug Interaction of Neomycin :Neomycin May Interact With Drugs Including Phenoxymethyl Penicillin, Digoxin, Methotrexate, Acarbose, Atracurium, Cyanocobalamin, Doxacurium, Fluorouracil, Gentamicin, Gestodene And Pancuronium Bromide, Neostigmine And Pyridostigmine. Caution Should Be Taken On The Use Of Neomycin With Drugs Known To Cause Kidney Related Problems, Including Aminoglycosides, Cephalosporins, Amphotericin, Ciclosporin, Capreomycin, Polymixins, Platinum Compounds, Teicoplanin And Vancomycin) And Ototoxicity (including Loop Diuretics, Capreomycin, Teicoplanin, Vancomycin And Possibly Platinum Compounds). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Neomycin :Urge To Vomit (nausea), Vomiting, Diarrhea, Increased Salivation, Stomatitis, Nephrotoxicity, Ototoxicity (hearing Problem), Rise In Serum Levels Of Liver Enzymes And Bilirubin, Imbalance Of Blood Components (blood Dyscrasias), Low Hemoglobin Or Red Blood Cells (hemolytic Anemia), Confusion, Tingling Or Burning Sensation (paresthesia), Disorientation, Rapid Movement Of The Eyeballs (nystagmus), Hypersensitivity Reactions Including Dermatitis, Itching (pruritus), Drug Fever And Anaphylaxis.

INTERACTIONS OF NEOMYCIN


How Neomycin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Neomycin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Neomycin

No Studies Found