Medicine : Sizen C

Name:Sizen C
Type:Cream
Manufacturer:Ind Swift Laboratories Ltd
Generic Use:Chlorhexidine Gluconate , Silver Sulphadiazine
Composition:Chlorhexidine Gluconate(0.2%w/w) , Silver Sulphadiazine(1%W/W)
Substitutes:silver star , silvindon plus , silvo , sizen c , argiept , silverex a(240gm) , glycigon , silverex (12gm) , silverex (240gm) , silverex (24gm) , silverex cream(240gm) , silverex cream(24gm) , silver star , silvindon plus , silvo , sizen c , argiept , silverex a(240gm) , glycigon , silverex (12gm) , silverex (240gm) , silverex (24gm) , silverex cream(240gm) , silverex cream(24gm)


Generic ( Chlorhexidine Gluconate )


Typical use Of Chlorhexidine Gluconate :Abrasion, Bladder Irrigation, Bleeding, Burns, Cuts, Gingivitis, Infected Cracked Skin, Minor Burns, Minor Scalds, Pleural And Peritoneal Irrigation, Skin Infections, Skin Lesions, Sunburn Blisters, Ulcers, Urethral Infection.
Mechanism of action of Chlorhexidine Gluconate :Chlorhexidine's Antimicrobial Effects Are Associated With The Attractions Between Chlorhexidine (cation) And Negatively Charged Bacterial Cells. After Chlorhexidine Is Absorpted Onto The Organism's Cell Wall, It Disrupts The Integrity Of The Cell Membrane And Causes The Leakage Of Intracellular Components Of The Organisms.
Drug Interaction of Chlorhexidine Gluconate :Chlorhexidine Is Known To Interact With Other Drugs Like Povidone-iodine. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Chlorhexidine Gluconate :Shortness Of Breadth, Hemolysis, Hypersensitivity Reactions, Photophobia, Slurred Speech, Allergic Skin Reactions, Nausea, Vomiting, Allergic Reactions, Photosensitivity, Skin Irritation, Skin Sensitization, Irritation Of Sensitive Tissues, Dermatitis, Taste Disturbances, Teeth Discoloration.

INTERACTIONS OF CHLORHEXIDINE GLUCONATE

How Chlorhexidine Gluconate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Chlorhexidine Gluconate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Chlorhexidine Gluconate

No Studies Found





Generic ( Silver Sulphadiazine )


Typical use Of Silver Sulphadiazine :Bacterial Infections, Burns And Scalds, Infections, Wounds.
Mechanism of action of Silver Sulphadiazine :Silver Sulfadiazine Acts Only On The Cell Membrane And Cell Wall To Produce Its Bactericidal Effect. Silver Ions Bind To Nucleophilic Amino Acids, As Well As Sulfhydryl, Amino, Imidazole, Phosphate, And Carboxyl Groups In Proteins, Causing Protein Denaturation And Enzyme Inhibition. Silver Binds To Surface Membranes And Proteins, Causing Proton Leaks In The Membrane, Leading To Cell Death. Sulfadiazine Is A Competitive Inhibitor Of Bacterial Para-aminobenzoic Acid (PABA), A Substrate Of The Enzyme Dihydropteroate Synthetase. The Inhibited Reaction Is Necessary In These Organisms For The Synthesis Of Folic Acid.
Drug Interaction of Silver Sulphadiazine :Silver Sulphadiazine Is Known To Interact With Other Drugs Like Povidone-iodine, Sulfacetamide Sodium, Tolbutamide, Trimethoprim. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Silver Sulphadiazine :Nephrotic Syndrome, Leucopenia, Glomerulonephritis.

INTERACTIONS OF SILVER SULPHADIAZINE

How Silver Sulphadiazine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Silver Sulphadiazine will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Silver Sulphadiazine

No Studies Found