Medicine : Simvas Ez

Name:Simvas Ez
Manufacturer:Micro Labs Ltd
Generic Use:Ezetimibe , Simvastatin
Composition:Ezetimibe(10 Mg) , Simvastatin(10 Mg)
Substitutes:simvas ez , simvotin ez(10mg) , simvotin ez(10mg) , simvas ez

Generic ( Ezetimibe )

Typical use Of Ezetimibe :Hypercholesterolaemia.
Mechanism of action of Ezetimibe :Ezetimibe Localizes And Appears To Act At The Brush Border Of The Small Intestine And Inhibits The Absorption Of Cholesterol. This Leads To A Decrease In The Delivery Of Intestinal Cholesterol To The Liver.
Drug Interaction of Ezetimibe :Ezetimibe Is Known To Interact With Other Drugs Like Sitosterol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ezetimibe :Pancreatitis, Muscular Weakness, Chest Pain, Dizziness, Headache, Diarrhea, Cough, Mild Stomach Pain.


How Ezetimibe will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ezetimibe will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ezetimibe

No Studies Found

Generic ( Simvastatin )

Typical use Of Simvastatin :Hyperlipidaemia,Cardiovascular Risk Reduction,Homozygous Familial Hypercholesterolaemia.
Mechanism of action of Simvastatin :Simvastatin Is A Prodrug Metabolised In The Liver To Form The Active ?-hydroxyacid Derivative. This Inhibits The Conversion Of HMG-CoA To Mevalonic Acid By Blocking HMG-CoA Reductase, An Early And Rate-limiting Step In Cholesterol Biosynthesis. It Reduces Total Cholesterol, LDL-cholesterol And Triglycerides And Increases HDL-cholesterol Levels.
Drug Interaction of Simvastatin :May Cause Slight Elevation Of Serum Digoxin. May Increase Risk Of Bleeding When Used With Coumarins And Fluindione.
Side effects of Simvastatin :Headache, Nausea, Flatulence, Heartburn, Abdominal Pain, Diarrhoea/constipation.


How Simvastatin will impact on Pregnancy ?

The Drug Should Not Be Used By Pregnant Women. Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown High Risk To Fetus. The Risk Of Drug Use In Pregnant Women Outweighs The Benefit.

How Simvastatin will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Simvastatin

No Studies Found