Medicine : Sidol

Name:Sidol
Type:Cream
Manufacturer:Ranbaxy Laboratories Ltd
Generic Use:Capsaicin , Methyl Salicylate , Piroxicam
Composition:Capsaicin(0.025% W/W) , Methyl Salicylate(5% W/W) , Piroxicam(0.5% W/w)
Substitutes:sidol , sidol , sidol


Generic ( Capsaicin )


Typical use Of Capsaicin :Treat Minor Aches And Pains Of The Muscles/joints (e.g., Arthritis, Backache, Sprains), Nerve Pain.
Mechanism of action of Capsaicin :Capsaicin Binds To A Receptor Called The Vanilloid Receptor Subtype 1 (VR1). VR1, Which Can Also Be Stimulated With Heat And Physical Abrasion, Permits Cations To Pass Through The Cell Membrane And Into The Cell When Activated. The Resulting Depolarization Of The Neuron Stimulates It To Signal The Brain.
Drug Interaction of Capsaicin :Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Capsaicin :Rash, Itching/swelling (especially Of The Face/tongue/throat), Severe Dizziness, Trouble Breathing, Warmth, Stinging, Or Burning On The Application Site May Occur.

INTERACTIONS OF CAPSAICIN

How Capsaicin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Capsaicin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Capsaicin

No Studies Found





Generic ( Methyl Salicylate )


Typical use Of Methyl Salicylate :Musculoskeletal Disorders, Peripheral Vascular Disease, Respiratory Tract Infections, Soft Tissue Disorders.
Mechanism of action of Methyl Salicylate :Methyl Salicylate Is Considered A Non-selective COX Inhibitorthat Is, It Inhibits Two Isoforms Of Cyclooxygenase, COX-1 And COX-2. The Analgesic, Antipyretic, And Anti-inflammatory Activity Of NSAIDs Appears To Be Achieved Mainly Through Inhibition Of COX-2, Whereas Inhibition Of COX-1 Would Be Responsible For Unwanted Effects On Platelet Aggregation And The Gastrointestinal Tract. Methyl Salicylate Directly And Irreversibly Inhibits The Activity Of Both Types Of Cyclo-oxygenases (COX-1 And COX-2) To Decrease The Formation Of Precursors Of Prostaglandins And Thromboxanes From Arachidonic Acid. Salicylate May Competitively Inhibit Prostaglandin Formation. Salicylate's Antirheumatic (nonsteroidal Anti-inflammatory) Actions Are A Result Of Its Analgesic And Anti-inflammatory Mechanisms.
Drug Interaction of Methyl Salicylate :Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Methyl Salicylate :Irritative Skin Reactions, Skin Ulcers, Stinging Of Skin.

INTERACTIONS OF METHYL SALICYLATE

How Methyl Salicylate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Methyl Salicylate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Methyl Salicylate

No Studies Found





Generic ( Piroxicam )


Typical use Of Piroxicam :Acute Gout, Acute Spasm And Spasm In Diagnostic Procedures, Ankylosing Spondylitis, Benign Gastric And Duodenal Ulceration, Duodenal Ulceration, Gout, Juvenile Chronic Arthritis, Musculoskeletal Disorders, Nausea And Vomiting (palliative Care), Osteoarthritis, Pain, Resistant Oedema, Rheumatoid Arthritis.
Mechanism of action of Piroxicam :Piroxicam Is A NSAID, Belonging To The Oxicam Group. It Inhibits Prostaglandin Synthesis, Reduces Fever By Acting On The Heat-regulating Center Of The Hypothalamus, Inhibits Platelet-aggregating Substance Thromboxane A2 And Reduces Pain Receptor Sensitivity. It Also Exerts Anti-inflammatory Effect By Lysosomal Stabilisation, Kinin And Leukotriene Production, Alteration Of Chemotactic Factors And Neutrophil Activation Inhibition.
Drug Interaction of Piroxicam :Ncreased Risk Of Hyperkalaemia When Used With ACE Inhibitors And Potassium-sparing Diuretics.
Side effects of Piroxicam :Dizziness, Headache, Palpitation, Insomnia, Confusion, VertigoX, Hearing Loss, Mood Swings, Paresthesias, Hypoglycemia.

INTERACTIONS OF PIROXICAM

How Piroxicam will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Piroxicam will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Piroxicam

No Studies Found