Generic ( Sibutramine )
|Typical use Of Sibutramine :||For The Treatment Of Obesity.|
|Mechanism of action of Sibutramine :||Sibutramine Produces Its Therapeutic Effects By Inhibition Of Norepinephrine (NE), Serotonin (5-hydroxytryptamine, 5-HT), And To A Lesser Extent, Dopamine Reuptake At The Neuronal Synapse. By Inhibiting The Reuptake Of These Neurotransmitters, Sibutramine Promotes A Sense Of Satiety And Decrease In Appetite, Thereby Reducing Food Intake. Data From Animal Studies Also Suggest That Sibutramine May Also Increase Energy Expenditure Through Thermogenic Effects In Both The Basal And Fed States, But This Has Not Been Confirmed In Humans.|
|Drug Interaction of Sibutramine :||Concurrent Admin Decreases The Absorption Of Ciprofloxacin. Not To Be Taken Concurrently With Oral Medications In Which The Safety And Efficacy Would Be Significantly Affected By Its Reduced Bioavailability.|
|Side effects of Sibutramine :||Nausea, Stomach Upset, Skin Rash, Acute Toxicity.|
INTERACTIONS OF SIBUTRAMINE
How Sibutramine will impact on Pregnancy ?Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Sibutramine will impact during lactation(breastfeeding) ?Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.
Medicine & Alcohol use and effect of SibutramineNo Studies Found