Medicine : Shaltop A Solution(50ml)

Name:Shaltop A Solution(50ml)
Type:Syrup
Manufacturer:Shalaks Pharmaceuticals Pvt Ltd
Generic Use:Minoxidil , Tretinoin , Azelaic Acid
Composition:Minoxidil(2% V/v) , Tretinoin(0.025% V/v) , Azelaic Acid(1.5% V/v)
Substitutes:shaltop a solution(50ml) , shaltop a solution(50ml) , shaltop a solution(50ml)


Generic ( Minoxidil )



Typical use Of Minoxidil :Alopecia Androgenetia (male Pattern Baldness) Alopecia Areata. Severe HTN Unresponsive To Standard Therapy.
Mechanism of action of Minoxidil :Minoxidil Is Thought To Promote The Survival Of Human Dermal Papillary Cells (DPCs) Or Hair Cells By Activating Both Extracellular Signal-regulated Kinase (ERK) And Akt And By Preventing Cell Death By Increasing The Ratio Of BCl-2/Bax. Minoxidil May Stimulate The Growth Of Human Hairs By Prolonging Anagen Through These Proliferative And Anti-apoptotic Effects On DPCs. Minoxidil, When Used As A Vasodilator, Acts By Opening Adenosine Triphosphate-sensitive Potassium Channels In Vascular Smooth Muscle Cells.
Drug Interaction of Minoxidil :Minoxidil Is Known To Interact With Other Drugs Like Clonidine (HCl), Nadolol, Nicorandil, Propranolol (HCl), Tretinoin. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Minoxidil :Oedema, Ascites, Tachycardia, Headache, Nausea, Palpitation, Flushing, Breast Tenderness, Hypertrichosis.

INTERACTIONS OF MINOXIDIL


How Minoxidil will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Minoxidil will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Minoxidil

No Studies Found






Generic ( Tretinoin )



Typical use Of Tretinoin :Acne Vulgaris, Promyelocytic Leukemia.
Mechanism of action of Tretinoin :Tretinoin Stimulates Mitosis And Turnover Of Follicular Epithelial Cells And Reduce Their Cohesiveness. This Facilitates Extrusion Of Existing Comedones And Prevents Formation Of New Comedone. It Also Exhibits Thinning Effect On The Stratum Corneum. In Acute Promyelocytic Leukaemia, It Induces Cellular Differentiation And Decreases Proliferations.
Drug Interaction of Tretinoin :Tretinoin Is Known To Interact With Other Drugs Like Alcohol, Benzoyl Peroxide, Minoxidil, Resorcinol, Retinol (Vitamin A), Salicylic Acid, Sulphur. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Tretinoin :Erythema, Irritation, Warmth Feeling.

INTERACTIONS OF TRETINOIN


How Tretinoin will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Tretinoin will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Tretinoin

No Studies Found






Generic ( Azelaic Acid )



Typical use Of Azelaic Acid : Acne Vulgaris.
Mechanism of action of Azelaic Acid : It Is Believed To Inhibit The Growth Of Susceptible Organisms (mainly Propionibacteria Acnes) On The Skin Surface, And Inhibits Follicular Keratinisation Thus Restricts The Development Of Comedones.
Drug Interaction of Azelaic Acid :No Data Regarding The Interactions Of Azelaic Acid Was Found.
Side effects of Azelaic Acid :Local Skin Irritation (e.g. Erythema, Scaling, Itching Or Burning). Hypopigmentation And Rarely, Photosensitivity Reactions.

INTERACTIONS OF AZELAIC ACID


How Azelaic Acid will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Azelaic Acid will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Azelaic Acid

No Studies Found