Medicine : Sebifin Plus(15gm)

Name:Sebifin Plus(15gm)
Type:Cream
Manufacturer:Ranbaxy Laboratories Ltd
Generic Use:Mometasone , Terbinafine
Composition:Mometasone(0.1%w/w) , Terbinafine(1%w/w)
Substitutes:sebifin plus(15gm) , tyza m cream(10gm) , hhlite , sebifin plus(15gm) , tyza m cream(10gm) , hhlite


Generic ( Mometasone )



Typical use Of Mometasone :Dermatoses.
Mechanism of action of Mometasone :Mometasone Bind With High Affinity To Specific Cytoplasmic Receptors. Inflammation Is Decreased By Diminishing The Release Of Leukocytic Acid Hydrolases, Prevention Of Macrophage Accumulation At Inflamed Sites, Interference With Leukocyte Adhesion To The Capillary Wall, Reduction Of Capillary Membrane Permeability, Reduction Of Complement Components, Inhibition Of Histamine And Kinin Release, And Interference With The Formation Of Scar Tissue. The Antiinflammatory Actions Of Corticosteroids Are Thought To Involve Phospholipase A2 Inhibitory Proteins, Lipocortins, Which Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes.
Drug Interaction of Mometasone :Mometasone Is Known To Interact With Other Drugs Like Itraconazole, Prednisolone And Prednisone. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Mometasone :Telangiectasia, Strias, Skin Atrophy, Decrease Synthesis Of Collagen In Dermis, Pruritus, Erythema, Burning, Allergic Contact Dermatitis, Tingling, Folliculitis, Acne, Paresthesias, Hypopigmentation.

INTERACTIONS OF MOMETASONE


How Mometasone will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Mometasone will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Mometasone

No Studies Found






Generic ( Terbinafine )



Typical use Of Terbinafine :To Treat Fungal Infections (ring Worm) Affecting Fingernails, Toenails And Skin.
Mechanism of action of Terbinafine :Terbinafine Stops Growth Of Fungi By Inhibiting Enzyme That Results In Reduced Formation Of Ergosterol, A Vital Component Of The Outer Protective Layer Of Fungi Which Is Essential For Fungal Growth.
Drug Interaction of Terbinafine :Rifampin Decreases Blood Levels Of Terbinafine. Desipramine, Cimetidine, Fluconazole, Ketoconazole, Amiodarone May Increase Blood Levels Of Terbinafine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Terbinafine :Fever, Headache, Burning, Irritation And Itching At Application Site, Vomiting, Urge To Vomit (nausea), Loss Of Appetite, Abdominal Pain, Indigestion, Skin Rashes, Redness And Itching Of Skin, Taste Disturbances, Musculoskeletal Pain (arthralgia, Myalgia), Liver Dysfunction (elevated Liver Enzymes), Inflammation Of Liver.

INTERACTIONS OF TERBINAFINE


How Terbinafine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Terbinafine will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Terbinafine

No Studies Found