Medicine : Safeguard Sr

Name:Safeguard Sr
Type:Tablet
Manufacturer:Pulse Pharmaceuticals
Generic Use:Diclofenac , Misoprostol
Composition:Diclofenac(100Mg) , Misoprostol(200mcg)
Substitutes:safeguard sr , safeguard , safeguard sr , safeguard


Generic ( Diclofenac )



Typical use Of Diclofenac :Diclofenac Is Used In The Treatment Of Painful Conditions Affecting The Joints And Muscles Such As Degenerative Joint Diseases (osteoarthritis), Autoimmune Diseases Of Joints (rheumatoid Arthritis, Ankylosing Spondylitis) Lower Back Pain, Sprains Or Bone Fractures, Inflammation In And Around Joints (frozen Shoulder), Tendon Inflammation, Tendon Sheath Swelling, Pain And Inflammation Associated With Diseases Such As Gout, Pain And Swelling Following Skeletal Muscle, Dental And Other Minor Surgery.
Mechanism of action of Diclofenac :Diclofenac Works By Blocking The Effect Of Chemicals Called Cyclooxygenase Enzymes. These Enzymes Help To Make Other Chemicals In The Body, Called Prostaglandins. Prostaglandins Are Produced At Sites Of Injury Or Damage, And Cause Pain And Swelling. By Blocking The Effect Of Cyclooxygenase Enzymes, Production Of Prostaglandins Are Reduced, Thus, Pain And Swelling Are Eased. 
Drug Interaction of Diclofenac :Diclofenac Should Be Avoided In Combination With Lithium, Blood Thinning Agents Such As Warfarin, Cyclosporine, Mifepristone, Methotrexate, Selective Serotonin Reuptake Inhibitors, Other Pain Killers, Corticosteroids, Diuretics, Tacrolimus, Zidovudine, And Quinolone Antibiotic Drugs. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Diclofenac :Ulcers In The Stomach And Intestine, Urge To Vomit, Vomiting, Excessive Passage Of Wind, Constipation, Indigestion, Abdominal Pain, Bloody Or Black Tar Like Stools, Vomiting Blood Or Dark Coffee Ground Like Material, Moth Ulcers, Severe Allergic Reactions, Water Retention And Swelling, Rise In Blood Pressure, Heart Failure, Damage To The Kidneys, Elevation Of Liver Enzymes, Inflammation Of Liver, Jaundice, Visual Disturbances, Ringing/buzzing In Ears, Headache, Other Nervous System Disorders, Decrease In The Blood Cells.

INTERACTIONS OF DICLOFENAC


How Diclofenac will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Diclofenac will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Diclofenac

No Studies Found






Generic ( Misoprostol )



Typical use Of Misoprostol :Termination Of Pregnancy (49 Days Or Less Duration).Cervical Ripening Before Surgical Termination Of Pregnancy In The 1st Trimester.Prevention And Treatment Of NSAID Associated Gastrointestinal Injury And Blood Loss.Benign Gastric And Duodenal Ulcer (not Usually Recommended).
Mechanism of action of Misoprostol :Misoprostol, A Synthetic Prostaglandin E1 Analogue, Exerts Its Antisecretory Activity By Directly Acting On Specific Prostaglandin Receptors Found On The Surface Of Gastric Parietal Cells. It Exerts Its Protective Effects On The Mucosa By Replacing The Prostaglandins Consumed During Prostaglandin-inhibiting Therapies E.g. NSAIDs.
Drug Interaction of Misoprostol :Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Misoprostol :Nausea, Stomach Upset, Skin Rash, Acute Toxicity.

INTERACTIONS OF MISOPROSTOL


How Misoprostol will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Misoprostol will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Misoprostol

No Studies Found