Medicine : Rubuphine (10mg)
|Manufacturer:||Rusan Pharma Ltd|
|Substitutes:||rubuphine (10mg) , nalfy (10mg) , ruffy (10mg)|
Generic ( Nalbuphine )
|Typical use Of Nalbuphine :||Adjunct To Prevent Relapse, Long Term Management Of Hereditary Angioedema, Moderate To Severe Pain.|
|Mechanism of action of Nalbuphine :||Nalbuphine Interacts With An Opiate Receptor Site In The CNS. The Opiate Antagonistic Effect May Result From Competitive Inhibition At The Opiate Receptor. Nalbuphine Is Thought Primarily To Be A Kappa Agonist. It Is Also A Partial Mu Antagonist Analgesic, With Some Binding To The Delta Receptor And Minimal Agonist Activity At The Sigma Receptor.|
|Drug Interaction of Nalbuphine :||Nalbuphine (HCl) Is Known To Interact With Other Drugs Like Alcohol, Alfentanil (HCl), Fentanyl (Citrate), Naloxone (HCl). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.|
|Side effects of Nalbuphine :||Sinus Tachycardia, Urticaria, Hypotension, Orthostatic Hypotension, Hypertension, Depression, Sinus Bradycardia, Syncope, Dizziness, Headache, Dyspnea, Dry Mouth, Blurred Vision, Pruritus, Vertigo, Sedation, Sweating, Flushing, Nausea And Vomiting.|
INTERACTIONS OF NALBUPHINE
How Nalbuphine will impact on Pregnancy ?Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Nalbuphine will impact during lactation(breastfeeding) ?Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
Medicine & Alcohol use and effect of NalbuphineNo Studies Found