Medicine : Rubizen (10mg)

Name:Rubizen (10mg)
Type:Injection
Manufacturer:Ranbaxy Laboratories Ltd
Generic Use:Epirubicin
Composition:Epirubicin(10 Mg)


Generic ( Epirubicin )



Typical use Of Epirubicin :Bladder Carcinoma, Breast Cancer, Gastric Cancer, Lung Cancer, Lymphoma, Ovarian Cancer.
Mechanism of action of Epirubicin :Epirubicin Has Antimitotic And Cytotoxic Activity. It Inhibits Nucleic Acid (DNA And RNA) And Protein Synthesis Through A Number Of Proposed Mechanisms Of Action: Epirubicin Forms Complexes With DNA By Intercalation Between Base Pairs, And It Inhibits Topoisomerase II Activity By Stabilizing The DNA-topoisomerase II Complex, Preventing The Religation Portion Of The Ligation-religation Reaction That Topoisomerase II Catalyzes. It Also Interferes With DNA Replication And Transcription By Inhibiting DNA Helicase Activity.
Drug Interaction of Epirubicin :Epirubicn Interacts With Cimetidine, Heparin,antineoplastic Drugs, Cardiotoxic Drugs, Radiation, Hepatoactive Drugs.
Side effects of Epirubicin :Fatigue, Nausea, Vomiting, Alopecia, Diarrhea, Mucositis, Urticaria, Hair Loss, Hot Flushes, Lassitude, Local Venous Flare.

INTERACTIONS OF EPIRUBICIN


How Epirubicin will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Epirubicin will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Epirubicin

No Studies Found