Medicine : Routine

Name:Routine
Type:Syrup
Manufacturer:Laxian Incorporation
Generic Use:Nicotinamide , Pyridoxine , Thiamine Hydrochloride , Riboflavin
Composition:Nicotinamide() , Pyridoxine(0.75mg) , Thiamine Hydrochloride() , Riboflavin(2.5mg)
Substitutes:routine , routine , routine , routine


Generic ( Nicotinamide )



Typical use Of Nicotinamide :To Treat Inflammatory Skin Disease Like Acne, Anxiety And Alzheimer’s Disease
Mechanism of action of Nicotinamide :Nicotinamide Is A Component Of Two Coenzymes, Which Bring About Tissue Respiration, Lipid, Amino Acid, Protein, And Purine Metabolism. Nicotinamide Lowers Blood Cholesterol And Triglyceride Levels By Inhibiting The Synthesis Of Very Low Density Lipoproteins.
Drug Interaction of Nicotinamide :Nicotinamide Is Known To Interact With Other Drugs Like Carbamazepine, Primidone By Reducing Its Clearance. It Also Interacts With Drugs Like Chloramphenicol, Phenytoin, Methotrexate, Penicillamine, Other Vitamins/nutritional Supplements, Antibiotics Like Ciprofloxacin, Levofloxacin And Tetracyclines. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Nicotinamide :Hepatotoxicity, Cholestasis, Portal Fibrosis, Headache, Fatigue, Urge To Vomit (nausea), Stomach Upset, Dizziness, Dry Hair, Diarrhea, Blurred Vision, Flushing And Rash.

INTERACTIONS OF NICOTINAMIDE


How Nicotinamide will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Nicotinamide will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Nicotinamide

No Studies Found






Generic ( Pyridoxine )



Typical use Of Pyridoxine :Pyridoxine Is Used To Treat Dysfunction Of Nerves Due To Isoniazid (anti-tuberculosis Drug), Idiopathic Sideroblastic Anemia (abnormal Blood Cells Produced By Bone Marrow) And Vitamin B6 Deficiency States.
Mechanism of action of Pyridoxine :Pyridoxine, A Vitamin B6 Supplement Is Required For The Proper Function Of Glucose, Fats, And Proteins In The Body. It Is Also Required For The Growth And Development Of The Brain, Nerves, Skin, And Many Other Parts Of The Body.
Drug Interaction of Pyridoxine :Pyridoxine May Interact With Other Drugs Like Isoniazid, Penicillamine, Oral Contraceptives, And Levodopa. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Pyridoxine :Long Term Administration Of Large Doses Is Associated With The Development Of Severe Peripheral Neuritis Resulting In Numbness And Pain, Usually In Hands And Feet.

INTERACTIONS OF PYRIDOXINE


How Pyridoxine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Pyridoxine will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Pyridoxine

No Studies Found






Generic ( Thiamine Hydrochloride )



Typical use Of Thiamine Hydrochloride :Lung Cancer And Pancreatic Cancer, Mild Chronic Deficiency, Severe Deficiency, Thiamine Deficiency Prophylaxis, Thiamine Deficiency Treatment.
Mechanism of action of Thiamine Hydrochloride :Thiamine Is Mainly The Transport Form Of The Vitamin, While The Active Forms Are Phosphorylated Thiamine Derivatives. There Are Five Known Natural Thiamine Phosphate Derivatives: Thiamine Monophosphate (ThMP), Thiamine Diphosphate (ThDP), Also Sometimes Called Thiamine Pyrophosphate (TPP), Thiamine Triphosphate (ThTP), And The Recently Discovered Adenosine Thiamine Triphosphate (AThTP), And Adenosine Thiamine Diphosphate. Each Derivative Has Unique Functions, However, Most Are Involved As Coenzymes.
Drug Interaction of Thiamine Hydrochloride :Thiamine Is Known To Interact With Other Drugs Like Aluminium Hydroxide And Oxide, Amiloride (HCl), Bumetanide, Chlorthalidone, Estradiol (Valerate), Estrogens Conjugated, Fluorouracil, Magnesium Carbonate, Magnesium Oxides And Hydroxides, Metformin (HCl), Phenobarbital Sodium, Phenobarbitone, Triamterene, Vecuronium (Br). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Thiamine Hydrochloride :Nausea, Urticaria, Gi Bleeding, Angioneurotic Edema, Restlessness, Pruritis, Pulmonary Edema, Hemorrhage, Cyanosis,

INTERACTIONS OF THIAMINE HYDROCHLORIDE


How Thiamine Hydrochloride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Thiamine Hydrochloride will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Thiamine Hydrochloride

No Studies Found






Generic ( Riboflavin )



Typical use Of Riboflavin :Arabinoflavinosis, Vitamin Deficiency.
Mechanism of action of Riboflavin :Binds To Riboflavin Hydrogenase, Riboflavin Kinase, And Riboflavin Synthase. Riboflavin Is The Precursor Of Flavin Mononucleotide (FMN, Riboflavin Monophosphate) And Flavin Adenine Dinucleotide (FAD). The Antioxidant Activity Of Riboflavin Is Principally Derived From Its Role As A Precursor Of FAD And The Role Of This Cofactor In The Production Of The Antioxidant Reduced Glutathione. Reduced Glutathione Is The Cofactor Of The Selenium-containing Glutathione Peroxidases Among Other Things. The Glutathione Peroxidases Are Major Antioxidant Enzymes. Reduced Glutathione Is Generated By The FAD-containing Enzyme Glutathione Reductase.
Drug Interaction of Riboflavin :Arabinoflavinosis, Vitamin Deficiency.
Side effects of Riboflavin :Discoloration Of Urine, Swelling Of Face, Difficulty Breathing, Swelling Of Lips And Tongue.

INTERACTIONS OF RIBOFLAVIN


How Riboflavin will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Riboflavin will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Riboflavin

No Studies Found