Medicine : Roletrad

Name:Roletrad
Type:Tablet
Manufacturer:Ranbaxy Laboratories Ltd
Generic Use:Loratadine , Pseudoephedrine
Composition:Loratadine(10mg) , Pseudoephedrine(180Mg)
Substitutes:roletrad , roletrad


Generic ( Loratadine )



Typical use Of Loratadine :Allergic Rhinitis, Acute Coryza, Allergic Dermatological Disorders.
Mechanism of action of Loratadine :Loratadine Competes With Free Histamine And Blocks The H1 Receptors. This Blocks The Action Of Endogenous Histamine, Which Subsequently Leads To Temporary Relief Of The Negative Symptoms (eg. Nasal Congestion, Watery Eyes) Brought On By Histamine. Loratadine Also Suppress The Release Of Leukotrienes From Human Lung Fragments.
Drug Interaction of Loratadine :Loratadine Is Known To Interact With Other Drugs Like Amprenavir, Clarithromycin, Erythromycin, Fluconazole, Fluoxetine (HCl), Ketoconazole, Procarbazine, Quinidine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Loratadine :Sinus Tachycardia, Hair Loss, Tinnitus, Hypotension, Insomnia, Blood Dyscrasias, Hypotension, Nausea, Vomiting, Tachycardia, Convulsions, Drowsiness, Hallucinations, Ataxia, Hyperpyrexia, Tremor, Ventricular Arrhythmias, Dizziness, Headache, Fatigue, Nausea, Vomiting, Diarrhea, Constipation, Dry Mouth, Pruritus, Sedation, Epigastric Pain.

INTERACTIONS OF LORATADINE


How Loratadine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Loratadine will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Loratadine

No Studies Found






Generic ( Pseudoephedrine )



Typical use Of Pseudoephedrine :Bronchospasm, Nasal Congestion, Rhinitis, Upper Respiratory Tract Infections.
Mechanism of action of Pseudoephedrine :Pseudoephedrine Is Both An ?-and ?-adrenergic Receptor Agonist. It Causes Vasoconstriction Via Direct Stimulation Of ?-adrenergic Receptors Of The Respiratory Mucosa. It Also Directly Stimulates ?-adrenergic Receptors Causing Bronchial Relaxation, Increased Heart Rate And Contractility.
Drug Interaction of Pseudoephedrine :Increased Risk Of Hypertension And Arrhythmias If Given With Cardiac Glycosides, Quinidine Or TCAs
Side effects of Pseudoephedrine :Drowsiness, Anorexia, Anxiety, Restlessness, Insomnia, Sleep DisturbancesX, Dry Mouth, Tremor.

INTERACTIONS OF PSEUDOEPHEDRINE


How Pseudoephedrine will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Pseudoephedrine will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Pseudoephedrine

No Studies Found