Medicine : Rapitoin Inj(50mg)

Name:Rapitoin Inj(50mg)
Type:Injection
Manufacturer:Emcure Pharmaceuticals Ltd
Generic Use:Fosphenytoin
Composition:Fosphenytoin(50 Mg)
Substitutes:rapitoin inj(50mg)


Generic ( Fosphenytoin )



Typical use Of Fosphenytoin :Status Epilepticus Prevention And Treatment Of Seizures During Neurosurgery.
Mechanism of action of Fosphenytoin : Fosphenytoin Acts On Sodium Channels On The Neuronal Cell Membrane, Limiting The Spread Of Seizure Activity And Reducing Seizure Propagation. By Promoting Sodium Efflux From Neurons, Fosphenytoin Tends To Stabilize The Threshold Against Hyperexcitability Caused By Excessive Stimulation Or Environmental Changes Capable Of Reducing Membrane Sodium Gradient. This Includes The Reduction Of Post-tetanic Potentiation At Synapses. Loss Of Post-tetanic Potentiation Prevents Cortical Seizure Foci From Detonating Adjacent Cortical Areas.
Drug Interaction of Fosphenytoin :Fosphenytoin Is Known To Interact With Other Drugs Like Acetazolamide (Na), Allopurinol, Amiodarone (HCl), Azapropazone, Bleomycin, Carbamazepine, Chloramphenicol, Chlorpheniramine (Maleate), Chlorpromazine (HCl), Cimetidine (HCl), Cisplatin, Co-trimoxazole, Cyclosporin A, Dexamethasone, Dextropropoxyphene, Diazoxide, Digoxin, Diltiazem (HCl), Disulfiram. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Fosphenytoin :Itching, Burning, Paresthesias, Hypotension, Bradycardia, Heart Block, Severe CV Reactions.

INTERACTIONS OF FOSPHENYTOIN


How Fosphenytoin will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Fosphenytoin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Fosphenytoin

No Studies Found