Medicine : Quadraijel
|Manufacturer:||Fourrts India Laboratories Pvt Ltd|
|Generic Use:||Chlorhexidine Gluconate , Lidocaine , Metronidazole Benzoate|
|Composition:||Chlorhexidine Gluconate(1%w/w) , Lidocaine(2%w/w) , Metronidazole Benzoate(1%w/w)|
|Substitutes:||quadraijel , quadraijel , quadraijel|
Generic ( Chlorhexidine Gluconate )
|Typical use Of Chlorhexidine Gluconate :||Abrasion, Bladder Irrigation, Bleeding, Burns, Cuts, Gingivitis, Infected Cracked Skin, Minor Burns, Minor Scalds, Pleural And Peritoneal Irrigation, Skin Infections, Skin Lesions, Sunburn Blisters, Ulcers, Urethral Infection.|
|Mechanism of action of Chlorhexidine Gluconate :||Chlorhexidine's Antimicrobial Effects Are Associated With The Attractions Between Chlorhexidine (cation) And Negatively Charged Bacterial Cells. After Chlorhexidine Is Absorpted Onto The Organism's Cell Wall, It Disrupts The Integrity Of The Cell Membrane And Causes The Leakage Of Intracellular Components Of The Organisms.|
|Drug Interaction of Chlorhexidine Gluconate :||Chlorhexidine Is Known To Interact With Other Drugs Like Povidone-iodine. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.|
|Side effects of Chlorhexidine Gluconate :||Shortness Of Breadth, Hemolysis, Hypersensitivity Reactions, Photophobia, Slurred Speech, Allergic Skin Reactions, Nausea, Vomiting, Allergic Reactions, Photosensitivity, Skin Irritation, Skin Sensitization, Irritation Of Sensitive Tissues, Dermatitis, Taste Disturbances, Teeth Discoloration.|
INTERACTIONS OF CHLORHEXIDINE GLUCONATE
How Chlorhexidine Gluconate will impact on Pregnancy ?Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Chlorhexidine Gluconate will impact during lactation(breastfeeding) ?Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
Medicine & Alcohol use and effect of Chlorhexidine GluconateNo Studies Found
Generic ( Lidocaine )
|Typical use Of Lidocaine :||Information Not Available.|
|Mechanism of action of Lidocaine :||Lidocaine Stabilizes The Neuronal Membrane By Inhibiting The Ionic Fluxes Required For The Initiation And Conduction Of Impulses Thereby Effecting Local Anesthetic Action. Lidocaine Alters Signal Conduction In Neurons By Blocking The Fast Voltage Gated Sodium (Na+) Channels In The Neuronal Cell Membrane That Are Responsible For Signal Propagation. With Sufficient Blockage The Membrane Of The Postsynaptic Neuron Will Not Depolarize And Will Thus Fail To Transmit An Action Potential. This Creates The Anaesthetic Effect By Not Merely Preventing Pain Signals From Propagating To The Brain But By Aborting Their Birth In The First Place.|
|Drug Interaction of Lidocaine :||Lignocaine Is Known To Interact With Other Drugs Like Alcuronium (Cl), Amphotericin B, Amprenavir, Atracurium (Besylate), Cimetidine (HCl), Edrophonium (Cl), Enflurane, Fosphenytoin, Halothane, Nadolol, Oxprenolol (HCl), Pentazocine, Propafenone (HCl). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.|
|Side effects of Lidocaine :||Allergy, Hypotension, Bronchospasm, Coma, Seizures, Hypertension, Tissue Necrosis, Angina, Sinus Bradycardia, Respiratory Depression, Blurred Vision, Tremors, Respiratory Depression, Bradycardia, Convulsions, Hypersensitivity, Cardiac Arrest, CNS Toxicity, Dizziness, Headache, Drowsiness, Nausea, Vomiting, Anxiety, Restlessness, Palpitation, Nervousness, Tinnitus, Abdominal Pain, Confusion.|
INTERACTIONS OF LIDOCAINE
How Lidocaine will impact on Pregnancy ?Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Lidocaine will impact during lactation(breastfeeding) ?Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
Medicine & Alcohol use and effect of LidocaineNo Studies Found
Generic ( Metronidazole Benzoate )
|Typical use Of Metronidazole Benzoate :||Acute Dental Infections, Acute Ulcerative Gingivitis, Amoebiasis, Anaerobic Bacterial Infection, Anaerobic Infections, Dysentery, Giardiasis, Lung Cancer And Pancreatic Cancer, Pelvic Inflammatory Disease, Protozoa Infection.|
|Mechanism of action of Metronidazole Benzoate :||Metronidazole Is A Prodrug. Unionized Metronidazole Is Selective For Anaerobic Bacteria Due To Their Ability To Intracellularly Reduce Metronidazole To Its Active Form. This Reduced Metronidazole Then Covalently Binds To DNA, Disrupt Its Helical Structure, Inhibiting Bacterial Nucleic Acid Synthesis And Resulting In Bacterial Cell Death.|
|Drug Interaction of Metronidazole Benzoate :||Acute Psychoses Or Confusion With Disulfiram. Additive/synergistic Effect With Other Antimicrobials.|
|Side effects of Metronidazole Benzoate :||Weakness, Dizziness, Vertigo, Headache, Anorexia, Diarrhea, Palpitation, Insomnia, Dry Mouth, Maculopapular Rash, Rashes.|
INTERACTIONS OF METRONIDAZOLE BENZOATE
How Metronidazole Benzoate will impact on Pregnancy ?The Drug Should Not Be Used By Pregnant Women. Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown High Risk To Fetus. The Risk Of Drug Use In Pregnant Women Outweighs The Benefit.
How Metronidazole Benzoate will impact during lactation(breastfeeding) ?Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.
Medicine & Alcohol use and effect of Metronidazole BenzoateNo Studies Found