Medicine : Psygrain

Name:Psygrain
Type:Tablet
Manufacturer:Psycoremedies
Generic Use:Caffeine , Ergotamine , Paracetamol
Composition:Caffeine(100Mg) , Ergotamine(1Mg) , Paracetamol(250Mg)
Substitutes:psygrain , psygrain , psygrain


Generic ( Caffeine )


Typical use Of Caffeine :To Treat Migraine Headaches And Mental Alertness. Caffeine Is Also Used In Combination With Pain Killers (aspirin And Paracetamol) And As A Supportive Treatment In Asthma.
Mechanism of action of Caffeine :Caffeine Acts By Stimulating The Brain (central Nervous System), Heart, And Muscles. It Also Improves The Effectiveness Of Pain-relievers Such As Paracetamol And Aspirin.
Drug Interaction of Caffeine :Taking Caffeine Along With Ephedrine Might Cause Excessive Brain Stimulation And Sometimes Serious Side Effects And Heart Problems. Phenytoin And Smoking With Caffeine May Decrease Level Of Caffeine In Blood. Certain Drugs Like Cimetidine, Disulfiram, Fluoroquinolones, Mexiletine And Oral Contraceptives May Enhance The Effects Of Caffeine By Increasing Its Concentration In Blood. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Caffeine :At Higher Doses (more Than 600 Mg Per Day), It May Cause Anxiety, Agitation, Diarrhea, Severe Urge To Vomit (nausea), Vomiting, Rapid Heart Rate (tachycardia), Rapid Heartbeat (palpitations), Inability To Sleep (insomnia), Restlessness, Nervousness, Involuntarily Shaking Of A Body Part (tremor) And Headache.

INTERACTIONS OF CAFFEINE

How Caffeine will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Caffeine will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Caffeine

No Studies Found





Generic ( Ergotamine )


Typical use Of Ergotamine :Prophylactic Treatment Of Vascular Headache, Vascular Headaches.
Mechanism of action of Ergotamine :Ergotamine Acts On Migraine By One Of Two Proposed Mechanisms: 1) Activation Of 5-HT1D Receptors Located On Intracranial Blood Vessels, Including Those On Arterio-venous Anastomoses, Leads To Vasoconstriction, Which Correlates With The Relief Of Migraine Headache, And 2) Activation Of 5-HT1D Receptors On Sensory Nerve Endings Of The Trigeminal System Results In The Inhibition Of Pro-inflammatory Neuropeptide Release.
Drug Interaction of Ergotamine :Ergotamine Is Known To Interact With Other Drugs Like Adrenaline, Amitriptyline (HCl), Amprenavir, Azithromycin, Clarithromycin, Ephedrine, Erythromycin, Glyceryl Trinitrate, Indinavir (Sulphate), Metaraminol, Methysergide (Hydrogen Maleate), Naratriptan, Nelfinavir, Nevirapine, Phenylephrine (HCl), Propranolol (HCl), Ritonavir, Sumatriptan, Tacrolimus. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ergotamine :Retroperitoneal Fibrosis, Pleuropulmonary Fibrosis, Endocardial Fibrosis, Myocardial Infarction, Renal Failure, Vascular Occlusions, Necrosis Of Bowel, Gangrene Of Extremities, Nausea, Vomiting, Tachycardia, Diarrhea, Coma, Confusion, Pallor, Cold Extremities.

INTERACTIONS OF ERGOTAMINE

How Ergotamine will impact on Pregnancy ?

The Drug Should Not Be Used By Pregnant Women. Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown High Risk To Fetus. The Risk Of Drug Use In Pregnant Women Outweighs The Benefit.

How Ergotamine will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Ergotamine

No Studies Found





Generic ( Paracetamol )


Typical use Of Paracetamol :Paracetamol Is Used For The Relief Of Mild To Moderate Pain In Conditions Such As Headache (including Migraine), Toothache, Ear Pain, Joint Pain, Pain Of Menstruation, Fever, Feverish Colds, And Flu.
Mechanism of action of Paracetamol :Paracetamol Is Categorized As An Analgesic (painkiller) And Antipyretic (fever Reducing) Drug. Paracetamol Reduces Pain By Increasing The Pain Threshold. It Reduces Fever By Acting On The Temperature-regulating Region Of Brain, Resulting In Increased Blood Flow Across The Skin, Sweating And Heat Loss.
Drug Interaction of Paracetamol :Cholestyramine, Metoclopramide And Domperidone May Alter The Effects Of Paracetamol. Use Of Paracetamol With Warfarin May Increase The Risk Of Bleeding. Paracetamol May Increase The Effects Of Chloramphenicol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Paracetamol :Side Effects Of Paracetamol Are Usually Rare, And Include Allergic Reactions Such As Shortness Of Breath, Abnormalities Of Blood Cells, Skin Reddening, Blisters Or Rash, Swollen Facial Features, Or A Runny Nose. Overdose (more Than 4 G In Adults And More Than 2 G In Children) May Cause Severe Liver Damage.

INTERACTIONS OF PARACETAMOL

How Paracetamol will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Paracetamol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Paracetamol

No Studies Found