Medicine : Prokinemps

Name:Prokinemps
Type:Tablet
Manufacturer:Rpg Life Sciences Ltd (acumed)
Generic Use:Cisapride , Simethicone
Composition:Cisapride(10mg) , Simethicone(125Mg)
Substitutes:cizapmps , prokin mps , prokinemps , cizapmps , prokin mps , prokinemps


Generic ( Cisapride )



Typical use Of Cisapride :Non Ulcer Dyspepsia, Disorders Associated With Decreased GI Motility,GERD
Mechanism of action of Cisapride :Cisapride Acts Through The Stimulation Of The Serotonin 5-HT4 Receptors Which Increases Acetylcholine Release In The Enteric Nervous System (specifically The Myenteric Plexus). This Results In Increased Tone And Amplitude Of Gastric (especially Antral) Contractions, Relaxation Of The Pyloric Sphincter And The Duodenal Bulb, And Increased Peristalsis Of The Duodenum And Jejunum Resulting In Accelerated Gastric Emptying And Intestinal Transit.
Drug Interaction of Cisapride :Cisapride Is Known To Interact With Other Drugs Like Amiodarone (HCl), Amitriptyline (HCl), Astemizole, Cimetidine (HCl), Clarithromycin, Cyclosporin A, Erythromycin, Fluconazole, Flurazepam (HCl), Halofantrine (HCl), Indinavir (Sulphate), Itraconazole, Ketoconazole, Mibefradil (Di HCl), Miconazole (Nitrate). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Cisapride :Cardiac Arrhythmias, Asthma, Diarrhea, Abdominal Cramps, Ventricular Arrhythmias, Q.T Interval Prolongation, Dizziness, Headache, Diarrhea,borborygmi.

INTERACTIONS OF CISAPRIDE


How Cisapride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Cisapride will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Cisapride

No Studies Found






Generic ( Simethicone )



Typical use Of Simethicone :Esophagitis, Flatulence, Gastric Bloating, Gastrocardiac Syndrome, Irritable Bowel Syndrome, Itchy Dermatitis, Meteorism, Oesophagitis, Peptic Ulcer, Postoperative Gas Pains.
Mechanism of action of Simethicone :Simethicone Releives Acidity By Lowering The Surface Tension Of Gas Bubbles.
Drug Interaction of Simethicone :Simethicone Is Known To Interact With Other Drugs Like Alginic Acid, Aluminium Hydroxide And Oxide, Strontium-89 Chloride. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Simethicone :Rashes, Hives, Diarrhea, Constipation, Itching, Burning, Heart Burn, Bloating, Stinging.

INTERACTIONS OF SIMETHICONE


How Simethicone will impact on Pregnancy ?

There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Simethicone will impact during lactation(breastfeeding) ?

There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Simethicone

No Studies Found