Medicine : Polybion Complete Syp(150ml)

Name:Polybion Complete Syp(150ml)
Type:Syrup
Manufacturer:E Merck India Limited
Generic Use:Nicotinamide , Ascorbic Acid
Composition:Nicotinamide(100 Mg) , Ascorbic Acid(150 Mg)
Substitutes:polybion complete syp(150ml) , polybion complete syp(150ml)


Generic ( Nicotinamide )



Typical use Of Nicotinamide :To Treat Inflammatory Skin Disease Like Acne, Anxiety And Alzheimer’s Disease
Mechanism of action of Nicotinamide :Nicotinamide Is A Component Of Two Coenzymes, Which Bring About Tissue Respiration, Lipid, Amino Acid, Protein, And Purine Metabolism. Nicotinamide Lowers Blood Cholesterol And Triglyceride Levels By Inhibiting The Synthesis Of Very Low Density Lipoproteins.
Drug Interaction of Nicotinamide :Nicotinamide Is Known To Interact With Other Drugs Like Carbamazepine, Primidone By Reducing Its Clearance. It Also Interacts With Drugs Like Chloramphenicol, Phenytoin, Methotrexate, Penicillamine, Other Vitamins/nutritional Supplements, Antibiotics Like Ciprofloxacin, Levofloxacin And Tetracyclines. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Nicotinamide :Hepatotoxicity, Cholestasis, Portal Fibrosis, Headache, Fatigue, Urge To Vomit (nausea), Stomach Upset, Dizziness, Dry Hair, Diarrhea, Blurred Vision, Flushing And Rash.

INTERACTIONS OF NICOTINAMIDE


How Nicotinamide will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Nicotinamide will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Nicotinamide

No Studies Found






Generic ( Ascorbic Acid )



Typical use Of Ascorbic Acid :Prevention And Treatment Of Scurvy, Scurvy, Vitamin Deficiency.
Mechanism of action of Ascorbic Acid :In Humans, An Exogenous Source Of Ascorbic Acid Is Required For Collagen Formation And Tissue Repair By Acting As A Cofactor In The Posttranslational Formation Of 4-hydroxyproline In -Xaa-Pro-Gly- Sequences In Collagens And Other Proteins. Ascorbic Acid Is Reversibly Oxidized To Dehydroascorbic Acid In The Body. These Two Forms Of The Vitamin Are Believed To Be Important In Oxidation-reduction Reactions. The Vitamin Is Involved In Tyrosine Metabolism, Conversion Of Folic Acid To Folinic Acid, Carbohydrate Metabolism, Synthesis Of Lipids And Proteins, Iron Metabolism, Resistance To Infections, And Cellular Respiration.
Drug Interaction of Ascorbic Acid :Interacts With Other Drugs Like Aminophylline, Bleomycin, Chloramphenicol, Chlorothiazide, Desogestrel, Erythromycin, Ethinyloestradiol, Hydrocortisone, Iron Salts, Levonorgestrel, Mestranol, Methylamphetamine, Nafcillin, Nitrofurantoin, Paracetamol, Rutin (Vitamin P), Sodium Bicarbonate, Sodium Succinate, Sulphadiazine.These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ascorbic Acid :Diarrhea, GI Disturbances. May Cause Acidification Of The Urine; Precipitation Of Urate, Cystine Or Oxalate Stones, Or Drugs In The Urinary Tract.

INTERACTIONS OF ASCORBIC ACID


How Ascorbic Acid will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ascorbic Acid will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ascorbic Acid

No Studies Found