Medicine : Polybion (400ml)

Name:Polybion (400ml)
Type:Syrup
Manufacturer:Merck Ltd
Generic Use:Nicotinamide , Vitamin B1 , Vitamin
Composition:Nicotinamide(15mg) , Vitamin B1(2mg) , Vitamin(0.75mg)
Substitutes:polybion (400ml) , polybion (400ml) , polybion (400ml)


Generic ( Nicotinamide )



Typical use Of Nicotinamide :To Treat Inflammatory Skin Disease Like Acne, Anxiety And Alzheimer’s Disease
Mechanism of action of Nicotinamide :Nicotinamide Is A Component Of Two Coenzymes, Which Bring About Tissue Respiration, Lipid, Amino Acid, Protein, And Purine Metabolism. Nicotinamide Lowers Blood Cholesterol And Triglyceride Levels By Inhibiting The Synthesis Of Very Low Density Lipoproteins.
Drug Interaction of Nicotinamide :Nicotinamide Is Known To Interact With Other Drugs Like Carbamazepine, Primidone By Reducing Its Clearance. It Also Interacts With Drugs Like Chloramphenicol, Phenytoin, Methotrexate, Penicillamine, Other Vitamins/nutritional Supplements, Antibiotics Like Ciprofloxacin, Levofloxacin And Tetracyclines. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Nicotinamide :Hepatotoxicity, Cholestasis, Portal Fibrosis, Headache, Fatigue, Urge To Vomit (nausea), Stomach Upset, Dizziness, Dry Hair, Diarrhea, Blurred Vision, Flushing And Rash.

INTERACTIONS OF NICOTINAMIDE


How Nicotinamide will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Nicotinamide will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Nicotinamide

No Studies Found






Generic ( Vitamin B1 )



Typical use Of Vitamin B1 :Vitamin B1 (Thiamine) Is Used As A Part Of The Treatment For Metabolic Disorders And Thiamine Deficiency Symptoms Including Beriberi (disease Affecting Heart And Nervous System) And Swelling Of The Nerves Associated With Pellagra (lack Of Niacin), Or Pregnancy, As Well As In Alcoholics And In People With Certain Types Of Genetic Diseases.
Mechanism of action of Vitamin B1 :Vitamin B1 Is A Water Soluble Vitamin And Is Involved In Many Body Functions, Including Nervous System And Muscular System, Digestion, And Carbohydrate Metabolism. Very Less Quantity Of Vitamin B1 Is Stored In The Body And Depletion Occurs Within 14 Days Of Intake. 
Drug Interaction of Vitamin B1 :Caution Is Advised In People Taking Drugs, Herbs Or Supplements That Lower Blood Pressure. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Vitamin B1 :Side Effects Are Unlikely To Occur With Intake Of Vitamin B1. In Some Cases, Low Blood Pressure, Rare Allergic Reactions And Skin Irritation May Occur.

INTERACTIONS OF VITAMIN B1


How Vitamin B1 will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Vitamin B1 will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Vitamin B1

No Studies Found






Generic ( Vitamin )



Typical use Of Vitamin :Information Not Available.
Mechanism of action of Vitamin :A Group Of Closely Related Chemical Compounds With Related Names -- Pyridoxine, Pyridoxal And Pyridoxamine -- That Are Transformed Within The Body To Yet Another Form Of Vitamin B6, Pyridoxal Phosphate, That Acts As A Coenzyme. (A Number Of Vitamins Serve As Coenzymes, Substances That Enhance The Action Of Enzymes And Thereby Aid In Catalyzing Biochemical Reactions.)
Drug Interaction of Vitamin :Your Doctor Or Pharmacist May Already Be Aware Of Any Possible Drug Interactions And May Be Monitoring You For Them. Do Not Start, Stop, Or Change The Dosage Of Any Medicine Before Checking With Your Doctor Or Pharmacist First.Before Using This Medication, Tell Your Doctor Or Pharmacist Of All Prescription And Nonprescription/herbal Products You May Use, Especially Of: "blood Thinners" (e.g., Warfarin, Heparin), High Blood Pressure Medicines.This Document Does Not Contain All Possible Interactions. Therefore, Before Using This Product, Tell Your Doctor Or Pharmacist Of All The Products You Use. Keep A List Of All Your Medications With You, And Share The List With Your Doctor And Pharmacist.
Side effects of Vitamin :Nausea, Stomach Upset, Skin Rash, Acute Toxicity.

INTERACTIONS OF VITAMIN


How Vitamin will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Vitamin will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Vitamin

No Studies Found