Medicine : Polybion (2ml)

Name:Polybion (2ml)
Type:Injection
Manufacturer:Merck Ltd
Generic Use:Pyridoxine Hydrochloride , Riboflavin Sodium Phosphate , Thiamine Hydrochloride
Composition:Pyridoxine Hydrochloride(4 Mg) , Riboflavin Sodium Phosphate(4 Mg) , Thiamine Hydrochloride(10 Mg)
Substitutes:polybion inj , polybion (2ml) , polybion inj , polybion (2ml) , polybion inj , polybion (2ml)


Generic ( Pyridoxine Hydrochloride )



Typical use Of Pyridoxine Hydrochloride :Pharmaceutical Aid
Mechanism of action of Pyridoxine Hydrochloride :Pharmaceutical Aid
Drug Interaction of Pyridoxine Hydrochloride :Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Pyridoxine Hydrochloride :Nausea, Stomach Upset, Skin Rash, Acute Toxicity.

INTERACTIONS OF PYRIDOXINE HYDROCHLORIDE


How Pyridoxine Hydrochloride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Pyridoxine Hydrochloride will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Pyridoxine Hydrochloride

No Studies Found






Generic ( Riboflavin Sodium Phosphate )



Typical use Of Riboflavin Sodium Phosphate :Arabinoflavinosis, Vitamin Deficiency.
Mechanism of action of Riboflavin Sodium Phosphate :Binds To Riboflavin Hydrogenase, Riboflavin Kinase, And Riboflavin Synthase. Riboflavin Is The Precursor Of Flavin Mononucleotide (FMN, Riboflavin Monophosphate) And Flavin Adenine Dinucleotide (FAD). The Antioxidant Activity Of Riboflavin Is Principally Derived From Its Role As A Precursor Of FAD And The Role Of This Cofactor In The Production Of The Antioxidant Reduced Glutathione. Reduced Glutathione Is The Cofactor Of The Selenium-containing Glutathione Peroxidases Among Other Things. The Glutathione Peroxidases Are Major Antioxidant Enzymes. Reduced Glutathione Is Generated By The FAD-containing Enzyme Glutathione Reductase.
Drug Interaction of Riboflavin Sodium Phosphate :Arabinoflavinosis, Vitamin Deficiency.
Side effects of Riboflavin Sodium Phosphate :Discoloration Of Urine, Swelling Of Face, Difficulty Breathing, Swelling Of Lips And Tongue.

INTERACTIONS OF RIBOFLAVIN SODIUM PHOSPHATE


How Riboflavin Sodium Phosphate will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Riboflavin Sodium Phosphate will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Riboflavin Sodium Phosphate

No Studies Found






Generic ( Thiamine Hydrochloride )



Typical use Of Thiamine Hydrochloride :Lung Cancer And Pancreatic Cancer, Mild Chronic Deficiency, Severe Deficiency, Thiamine Deficiency Prophylaxis, Thiamine Deficiency Treatment.
Mechanism of action of Thiamine Hydrochloride :Thiamine Is Mainly The Transport Form Of The Vitamin, While The Active Forms Are Phosphorylated Thiamine Derivatives. There Are Five Known Natural Thiamine Phosphate Derivatives: Thiamine Monophosphate (ThMP), Thiamine Diphosphate (ThDP), Also Sometimes Called Thiamine Pyrophosphate (TPP), Thiamine Triphosphate (ThTP), And The Recently Discovered Adenosine Thiamine Triphosphate (AThTP), And Adenosine Thiamine Diphosphate. Each Derivative Has Unique Functions, However, Most Are Involved As Coenzymes.
Drug Interaction of Thiamine Hydrochloride :Thiamine Is Known To Interact With Other Drugs Like Aluminium Hydroxide And Oxide, Amiloride (HCl), Bumetanide, Chlorthalidone, Estradiol (Valerate), Estrogens Conjugated, Fluorouracil, Magnesium Carbonate, Magnesium Oxides And Hydroxides, Metformin (HCl), Phenobarbital Sodium, Phenobarbitone, Triamterene, Vecuronium (Br). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Thiamine Hydrochloride :Nausea, Urticaria, Gi Bleeding, Angioneurotic Edema, Restlessness, Pruritis, Pulmonary Edema, Hemorrhage, Cyanosis,

INTERACTIONS OF THIAMINE HYDROCHLORIDE


How Thiamine Hydrochloride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Thiamine Hydrochloride will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Thiamine Hydrochloride

No Studies Found