Medicine : Pipzo (4.5gm)

Name:Pipzo (4.5gm)
Type:Injection
Manufacturer:Alkem Laboratories Ltd
Generic Use:Piperacillin , Tazobactam
Composition:Piperacillin(4g) , Tazobactam(500mg)
Substitutes:perabactum 1(500mg) , zosyn (4.5gm) , pipzo (4.5gm) , pybactum (4.5gm) , tazact (1.125) , zosyn (45gm) , perabactum 1(500mg) , zosyn (4.5gm) , pipzo (4.5gm) , pybactum (4.5gm) , tazact (1.125) , zosyn (45gm)


Generic ( Piperacillin )



Typical use Of Piperacillin :Serious Infections Caused By Pseudomonas, Proteus, Klebsiella E.g. Burns, Urinary Tract Infection, Septicaemia Used Mainly In Neutropenia/immunocompromised Patients.
Mechanism of action of Piperacillin :Piperacillin Binds To Specific Penicillin-binding Proteins (PBPs) Located Inside The Bacterial Cell Wall, Piperacillin Inhibits The Third And Last Stage Of Bacterial Cell Wall Synthesis. Cell Lysis Is Then Mediated By Bacterial Cell Wall Autolytic Enzymes Such As Autolysins.
Drug Interaction of Piperacillin :Piperacillin (Na) Is Known To Interact With Other Drugs Like Arbekacin, Atracurium (Besylate), Cefoxitin, Chloramphenicol, Floxacillin (Na), Methotrexate, Probenecid, Tobramycin, Warfarin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Piperacillin :Prolongation Of Bleeding Time, Anaphylaxis, Nausea, Vomiting, Diarrhea, Thrombophlebitis.

INTERACTIONS OF PIPERACILLIN


How Piperacillin will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Piperacillin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Piperacillin

No Studies Found






Generic ( Tazobactam )



Typical use Of Tazobactam :It Is Indicated For The Treatment Of Patients With Moderate To Severe Infections Caused By Piperacillin-resistant, Piperacillin/tazobactamsusceptible, ?-lactamase Producing Strains Of The Designated Microorganisms (Appendicitis (complicated By Rupture Or Abscess) And Peritonitis Caused By Piperacillin-resistant, ?-lactamase Producing Strains Of Escherichia Coli Or The Following Members Of The Bacteroides Fragilis Group: B. Fragilis, B. Ovatus, B. Thetaiotaomicron, Or B. Vulgatus).
Mechanism of action of Tazobactam :Tazobactum Inhibits The Action Of Bacterial ?-lactamases That Would Normally Degrade Piperacillin And Extend The Spectrum Of ?-lactam Antibiotics.
Drug Interaction of Tazobactam :Tazobactam Is Known To Interact With Other Drugs Like Arbekacin, Atracurium (Besylate), Cefoxitin, Chloramphenicol, Floxacillin (Na), Methotrexate, Probenecid, Tobramycin, Warfarin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Tazobactam :Phlebitis, Injection Site Reaction, Pain, Inflammation, Thrombophlebitis, Edema.

INTERACTIONS OF TAZOBACTAM


How Tazobactam will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Tazobactam will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Tazobactam

No Studies Found