Medicine : Perigard Df

Name:Perigard Df
Type:Tablet
Manufacturer:Glenmark Pharmaceuticals Ltd
Generic Use:Indapamide , Perindopril
Composition:Indapamide(1.2 Mg) , Perindopril(2 Mg)
Substitutes:perigard df , perigard df


Generic ( Indapamide )



Typical use Of Indapamide :Hypertension, Oedema.
Mechanism of action of Indapamide :Indapamide Blocks The Slow Component Of Delayed Rectifier Potassium Current Without Altering The Rapid Component Or The Inward Rectifier Current. Specifically It Blocks Or Antagonizes The Action The Proteins KCNQ1 And KCNE1. Indapamide Is Also Thought To Stimulate The Synthesis Of The Vasodilatory Hypotensive Prostaglandin PGE2.
Drug Interaction of Indapamide :Hypertension, Oedema.
Side effects of Indapamide :Headache, Dizziness, Weakness, Drowsiness, Fatigue, Agitation, Nervousness, Anorexia, Nausea, Vomiting, Pain, Diarrhoea, Constipation, Orthostatic Hypotension, Palpitations.

INTERACTIONS OF INDAPAMIDE


How Indapamide will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Indapamide will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Indapamide

No Studies Found






Generic ( Perindopril )



Typical use Of Perindopril :Congestive Heart Failure, Heart Failure, Heart Failure (adjunct), Hypertension, Myocardial Infarction.
Mechanism of action of Perindopril :Perindoprilat, The Active Metabolite Of Perindopril, Competes With ATI For Binding To ACE And Inhibits And Enzymatic Proteolysis Of ATI To ATII. Decreasing ATII Levels In The Body Decreases Blood Pressure By Inhibiting The Pressor Effects Of ATII As Described In The Pharmacology Section Above. Perindopril Also Causes An Increase In Plasma Renin Activity Likely Due To A Loss Of Feedback Inhibition Mediated By ATII On The Release Of Renin And/or Stimulation Of Reflex Mechanisms Via Baroreceptors.
Drug Interaction of Perindopril :Perindopril Is Known To Interact With Other Drugs Like Acetohexamide, Alcohol, Amiloride (HCl), Baclofen, Betamethasone, Bumetanide, Carbenoxolone (Na), Chlorpromazine (HCl), Chlorpropamide, Cyclosporin A, Dexamethasone, Indomethacin, Lithium, Phenylbutazone, Piretanide, Prazosin, Terazosin, Tolbutamide, Torasemide, Triamterene. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Perindopril :Thrombocytopenia, Leucopenia, Neutropenia, Paresthesia, Myocardial Infarction, Dizziness, Headache, Fatigue, Nausea, Diarrhea, Constipation, Tinnitus, Abdominal Pain, Rashes, Epigastric Discomfort, Dyspepsia, Cough, Asthenia, Dry Cough.

INTERACTIONS OF PERINDOPRIL


How Perindopril will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Perindopril will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Perindopril

No Studies Found