Medicine : Parafon

Name:Parafon
Type:Tablet
Manufacturer:Johnson & Johnson Ltd
Generic Use:Acetaminophen , Chlorzoxazone
Composition:Acetaminophen(300mg) , Chlorzoxazone(250mg)
Substitutes:parafon , parafon


Generic ( Acetaminophen )



Typical use Of Acetaminophen :Analgesic, Antipyretic.
Mechanism of action of Acetaminophen :Acetaminophen Exhibits Analgesic Action By Peripheral Blockage Of Pain Impulse Generation. It Produces Antipyresis By Inhibiting The Hypothalamic Heat-regulating Centre. Its Weak Anti-inflammatory Activity Is Related To Inhibition Of Prostaglandin Synthesis In The CNS.
Drug Interaction of Acetaminophen :Reduced Absorption Of Cholestyramine Within 1 Hr Of Admin. Accelerated Absorption With Metoclopramide. Decreased Effect With Barbiturates, Carbamazepine, Hydantoins, Rifampicin And Sulfinpyrazone. Paracetamol May Increase Effect Of Warfarin.
Side effects of Acetaminophen :Nausea, Allergic Reactions, Skin Rashes, Acute Renal Tubular Necrosis

INTERACTIONS OF ACETAMINOPHEN


How Acetaminophen will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Acetaminophen will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Acetaminophen

No Studies Found






Generic ( Chlorzoxazone )



Typical use Of Chlorzoxazone :To Relieve Pain And Stiffness Caused By Muscle Strains And Sprains. It Is Used In Combination With Physical Therapy, Painkillers And Rest.
Mechanism of action of Chlorzoxazone :Chlorzoxazone Causes Muscle Relaxation And Reduces Muscle Stiffness By Blocking Nerve Impulses (or Pain Sensations) That Are Sent To The Brain.
Drug Interaction of Chlorzoxazone :Chlorzoxazone Potentiates The Effect Of Other Drugs That Cause Drowsiness Including Cetirizine, Diphenhydramine, Drugs For Sleep Or Anxiety (alprazolam, Diazepam, Zolpidem), Other Muscle Relaxants, Atorvastatin, Esomeprazole, Topiramate, Cholecalciferol And Narcotic Pain Relievers (such As Codeine). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Chlorzoxazone :Increased Sleepiness, Dizziness, Headache, Weakness, Stomach Upset And Restlessness.

INTERACTIONS OF CHLORZOXAZONE


How Chlorzoxazone will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Chlorzoxazone will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Chlorzoxazone

No Studies Found