Medicine : Panderm Plus Cream(15gm)

Name:Panderm Plus Cream(15gm)
Type:Cream
Manufacturer:Macleods Pharmaceuticals Ltd
Generic Use:Ofloxacin , Ornidazole , Terbinafine , Clobetasole Propionate
Composition:Ofloxacin(0.75% W/w) , Ornidazole(2% W/w) , Terbinafine(1% W/w) , Clobetasole Propionate(0.05% W/w)
Substitutes:panderm plus cream(15gm) , panderm plus cream(15gm) , panderm plus cream(15gm) , panderm plus cream(15gm)


Generic ( Ofloxacin )



Typical use Of Ofloxacin :To Treat Bacterial Infections Including Urinary Tract Infections, Respiratory Infections , Skin And Soft Tissue Infections, Sexually Transmitted Infections (of Urethra And Cervix) And External Eye Infections (conjuctivitis).
Mechanism of action of Ofloxacin :Ofloxacin Belongs To The Group Of Medicines Called Fluoroquinolone Antibiotics. They Cure The Infection By Inhibiting The DNA Formation And Killing The Bacteria.
Drug Interaction of Ofloxacin :Ofloxacin May Interact With Other Drugs Including Drugs That Are Used To Treat The Abnormal Rate And Rhythm Of Heart (antiarrythmics Viz Quindine, Hydroquindine, Disopyramide, Amiodarone, Sotalol, Dofetilide, Ibutilide), Tricyclic Anti-depressants , Antibiotics (azithromycin) And Some Anti-psychotics. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ofloxacin :When Used As Eye-drops, Side Effects Include Visual Disturbance, Tearing, Mild Stinging, Burning Or Pricking, Irritation, Ocular Discomfort, Inflammation, Redness, Itching, Allergic Reactions In The Eye (including Itchiness Of The Eye And Eyelid), Sensitivity To Light, Eye Swelling. When Used Orally, Side Effects Include Dizziness, Nausea, Allergic Reactions (swelling Of Face, Lips Or Other Parts Of The Body; Rash Or Itching On The Skin; Swelling Of The Mouth, Tongue Or Throat That Can Obstruct The Airways Which May Cause Wheezing, Difficulty Swallowing, Breathing Or Shortness Of Breath; Severe Sudden Life-threatening Allergic Reaction), Swelling Of The Face.

INTERACTIONS OF OFLOXACIN


How Ofloxacin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ofloxacin will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Ofloxacin

No Studies Found






Generic ( Ornidazole )



Typical use Of Ornidazole :To Treat Certain Types Of Vaginal, Urinary Tract And Intestinal Infections, Or Some Specific Infections That Are In The Body, Which May Be Caused By Anaerobic Bacteria (bacteria That Do Not Use Oxygen) Or Amoeba. It Is Also Used For Preventive (prophylactic) Treatment During Surgery, Treat Amoebiasis, Amoebic Dysentery, Bacterial Infection Of Vagina (bacterial Vaginosis), Diarrhea Caused By Protozoan Parasite (giardiasis), And Acute Infections Of Vagina And/or Urethra (trichomoniasis).
Mechanism of action of Ornidazole :Ornidazole Is Active Against The Protozoa And Anaerobic Bacteria That Are Causing The Infections. Action Mechanism Is Associated With Inhibiting The Structure Of DNA In Susceptible Microorganisms.
Drug Interaction of Ornidazole :Ornidazole May Interact With Oral Anticoagulants (warfarin) And Muscle-relaxant (vecuronium Bromide). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ornidazole :Drowsiness, Dizziness, Headache, Shaking, Rigidity, Poor Coordination, Fits, Tiredness, Temporary Loss Of Consciousness, Fainting, Sensation Of Spinning Or Rotation (vertigo), Urge To Vomit (nausea), Vomiting, Pain In Abdomen, Taste Disturbances, Skin Reactions Like Rash, Itching And Inflammation.

INTERACTIONS OF ORNIDAZOLE


How Ornidazole will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ornidazole will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ornidazole

No Studies Found






Generic ( Terbinafine )



Typical use Of Terbinafine :To Treat Fungal Infections (ring Worm) Affecting Fingernails, Toenails And Skin.
Mechanism of action of Terbinafine :Terbinafine Stops Growth Of Fungi By Inhibiting Enzyme That Results In Reduced Formation Of Ergosterol, A Vital Component Of The Outer Protective Layer Of Fungi Which Is Essential For Fungal Growth.
Drug Interaction of Terbinafine :Rifampin Decreases Blood Levels Of Terbinafine. Desipramine, Cimetidine, Fluconazole, Ketoconazole, Amiodarone May Increase Blood Levels Of Terbinafine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Terbinafine :Fever, Headache, Burning, Irritation And Itching At Application Site, Vomiting, Urge To Vomit (nausea), Loss Of Appetite, Abdominal Pain, Indigestion, Skin Rashes, Redness And Itching Of Skin, Taste Disturbances, Musculoskeletal Pain (arthralgia, Myalgia), Liver Dysfunction (elevated Liver Enzymes), Inflammation Of Liver.

INTERACTIONS OF TERBINAFINE


How Terbinafine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Terbinafine will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Terbinafine

No Studies Found






Generic ( Clobetasole Propionate )



Typical use Of Clobetasole Propionate :Skin Infection
Mechanism of action of Clobetasole Propionate :The Precise Mechanism Of The Antiinflammatory Activity Of Topical Steroids In The Treatment Of Steroid-responsive Dermatoses, In General, Is Uncertain. However, Corticosteroids Are Thought To Act By The Induction Of Phospholipase A2 Inhibitory Proteins, Collectively Called Lipocortins. It Is Postulated That These Proteins Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes By Inhibiting The Release Of Their Common Precursor Arachidonic Acid. Arachidonic Acid Is Released From Membrane Phospholipids By Phospholipase A2. Initially, However, Clobetasol, Like Other Corticosteroids, Bind To The Glucocorticoid Receptor, Which Complexes, Enteres The Cell Nucleus And Modifies Genetic Transcription (transrepression/transactivation).
Drug Interaction of Clobetasole Propionate :If Overdose Is Suspected, Contact Your Physician.
Side effects of Clobetasole Propionate :Headache, Fatigue, Nausea, Constipation, Dry Mouth, Sedation, Skin Rash, Gastralgia.

INTERACTIONS OF CLOBETASOLE PROPIONATE


How Clobetasole Propionate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Clobetasole Propionate will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Clobetasole Propionate

No Studies Found