Generic ( Paclitaxel )

Typical use Of Paclitaxel :Breast Cancer, Ovarian Cancer, Primary Ovarian Cancer.
Mechanism of action of Paclitaxel :Paclitaxel Binds To The ? Subunit Of Tubulin. Tubulin Is The "building Block" Of Mictotubules, And The Binding Of Paclitaxel Locks These Building Blocks In Place. The Resulting Microtubule/paclitaxel Complex Does Not Have The Ability To Disassemble. This Adversely Affects Cell Function Because The Shortening And Lengthening Of Microtubules (termed Dynamic Instability) Is Necessary For Their Function As A Transportation Highway For The Cell.
Drug Interaction of Paclitaxel :Paclitaxel Is Known To Interact With Other Drugs Like Cisplatin, Doxorubicin (HCl), Fluorouracil, Ketoconazole, Podophyllum, Rotavirus Vaccine, Strontium-89 Chloride, Trastuzumab. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Paclitaxel :Cardiac Arrhythmias, Anemia, Bradycardia, AV-block, Neutropenia, Bone Marrow Depression, Nausea, Vomiting, Diarrhea, Mucositis, Myalgia, Hypotension, Arthralgia, Thrombocytopenia, UTI.


How Paclitaxel will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Paclitaxel will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Paclitaxel

No Studies Found