Medicine : Oxalgin Nano Gel(50gm)

Name:Oxalgin Nano Gel(50gm)
Type:Gel
Manufacturer:Cadila Pharmaceuticals Ltd
Generic Use:Diclofenac Sodium , Menthol , Methyl Salicylate
Composition:Diclofenac Sodium(10 Mg) , Menthol(50 Mg/1 G) , Methyl Salicylate(150 Mg)
Substitutes:oxalgin nano gel(50gm) , oxalgin nano gel(50gm) , oxalgin nano gel(50gm)


Generic ( Diclofenac Sodium )



Typical use Of Diclofenac Sodium :Bacterial Eye Infections And Inflammation
Mechanism of action of Diclofenac Sodium :This Medication Is An NSAID, Prescribed For Severe Pain. This Medication Decreases The Hormones That Cause Inflammation And Pain In The Body.
Drug Interaction of Diclofenac Sodium :Diclofenac, Like Other NSAIDs Is Associated With Several Suspected Or Probable Interactions That Affect The Action Of Other Drugs. Some Examples Are Discussed Below. Diclofenac May Increase The Blood Levels Of Lithium (Eskalith) By Reducing The Excretion Of Lithium By The Kidneys. Increased Levels Of Lithium May Lead To Lithium Toxicity. Diclofenac May Reduce The Blood Pressure Lowering Effects Of Blood Pressure Medications. This May Occur Because Prostaglandins Play A Role In The Regulation Of Blood Pressure. When Diclofenac Is Used In Combination With Aminoglycoside Antibiotics [for Example, Gentamicin (Garamycin)] The Blood Levels Of The Aminoglycoside May Increase, Presumably Because The Elimination Of Aminoglycosides From The Body Is Reduced. This May Lead To More Aminoglycoside-related Side Effects. Individuals Taking Oral Blood Thinners Or Anticoagulants [for Example,warfarin (Coumadin)] Should Avoid Diclofenac Because Diclofenac Also Thins The Blood, And Excessive Blood Thinning May Lead To Bleeding. Combining NSAIDs With Methotrexate (Rheumatrex, Trexall) May Reduce The Elimination Of Methotrexate From The Body And Result In Increased Side Effects From Methotrexate.
Side effects of Diclofenac Sodium :Nausea, Stomach Upset, Skin Rash, Acute Toxicity.

INTERACTIONS OF DICLOFENAC SODIUM


How Diclofenac Sodium will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Diclofenac Sodium will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Diclofenac Sodium

No Studies Found






Generic ( Menthol )



Typical use Of Menthol :Pharmaceutical Aid
Mechanism of action of Menthol :Menthol Primarily Activates The Cold-sensitive TRPM8 Receptors In The Skin. Menthol, After Topical Application, Causes A Feeling Of Coolness Due To Stimulation Of 'cold' Receptors By Inhibiting Ca++ Currents Of Neuronal Membranes. It May Also Yield Analgesic Properties Via Kappa-opioid Receptor Agonism.
Drug Interaction of Menthol :Menthol Is Known To Interact With Other Drugs Like Alcohol. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Menthol :Nystagmus, Contact Dermatitis, Apnea. Menthol Produces Potentially Life-threatening Effects Which Include Coma. Overdosage Of Menthol Include Irregularities In Heart Rhythm. The Symtomatic Adverse Effects Produced By Menthol Such As Vertigo, Drowsiness, Ataxia, Abdominal Pain, Nausea And Vomiting.

INTERACTIONS OF MENTHOL


How Menthol will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Menthol will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Menthol

No Studies Found






Generic ( Methyl Salicylate )



Typical use Of Methyl Salicylate :Musculoskeletal Disorders, Peripheral Vascular Disease, Respiratory Tract Infections, Soft Tissue Disorders.
Mechanism of action of Methyl Salicylate :Methyl Salicylate Is Considered A Non-selective COX Inhibitor¬Ěthat Is, It Inhibits Two Isoforms Of Cyclooxygenase, COX-1 And COX-2. The Analgesic, Antipyretic, And Anti-inflammatory Activity Of NSAIDs Appears To Be Achieved Mainly Through Inhibition Of COX-2, Whereas Inhibition Of COX-1 Would Be Responsible For Unwanted Effects On Platelet Aggregation And The Gastrointestinal Tract. Methyl Salicylate Directly And Irreversibly Inhibits The Activity Of Both Types Of Cyclo-oxygenases (COX-1 And COX-2) To Decrease The Formation Of Precursors Of Prostaglandins And Thromboxanes From Arachidonic Acid. Salicylate May Competitively Inhibit Prostaglandin Formation. Salicylate's Antirheumatic (nonsteroidal Anti-inflammatory) Actions Are A Result Of Its Analgesic And Anti-inflammatory Mechanisms.
Drug Interaction of Methyl Salicylate :Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Methyl Salicylate :Irritative Skin Reactions, Skin Ulcers, Stinging Of Skin.

INTERACTIONS OF METHYL SALICYLATE


How Methyl Salicylate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Methyl Salicylate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Methyl Salicylate

No Studies Found