Medicine : Otimef Spas

Name:Otimef Spas
Type:Tablet
Manufacturer:John Walter Labs
Generic Use:Mefenamic Acid , Paracetamol
Composition:Mefenamic Acid(500mg) , Paracetamol(450mg)
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Generic ( Mefenamic Acid )


Typical use Of Mefenamic Acid :To Treat Mild To Moderate Pain During Periods(dysmenorrhea), Heavy Bleeding During Periods (Menorrhagia) Due To Any Cause, Fever, Inflammation, Migraine Headache, Tooth Pain, Muscle And Joint Pain (arthritis), Post-operative Pain, Post Child Birth Pain, And Rheumatoid Arthritis.
Mechanism of action of Mefenamic Acid :Mefenamic Acid Acts By Blocking The Effect Of Enzymes Called Cyclo-oxygenase (COX). By Blocking The Effect Of COX Enzymes, Prostaglandins (a Hormone-like Substance) Production Is Reduced Resulting In Ease Of Pain And Inflammation.
Drug Interaction of Mefenamic Acid :Mefenamic Acid Is Known To Interact With Drugs Like Warfarin, Lithium, Digoxin, Captopril, Enalapril, Sulfapyridine, Probenecid, Methotrexate, Ciclosporin, Prednisone, Torasemide And Antidiabetic Medications. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Mefenamic Acid :Urge To Vomit (nausea), Diarrhea, Excessive Passing Of Gas, Abdominal Pain, Stomach Ulcer, Constipation, Inflammation Of Pancreas, Swelling, Irritation Of Skin, Bleeding In Stomach, Proteinuria, Jaundice, Breakdown Of Blood Cells, Inflammation Of Intestine, Indigestion, Heartburn, Dizziness, Headache, Drowsiness, Skin Rashes And Increased Level Of Liver Enzymes.

INTERACTIONS OF MEFENAMIC ACID

How Mefenamic Acid will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Mefenamic Acid will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Mefenamic Acid

No Studies Found





Generic ( Paracetamol )


Typical use Of Paracetamol :Paracetamol Is Used For The Relief Of Mild To Moderate Pain In Conditions Such As Headache (including Migraine), Toothache, Ear Pain, Joint Pain, Pain Of Menstruation, Fever, Feverish Colds, And Flu.
Mechanism of action of Paracetamol :Paracetamol Is Categorized As An Analgesic (painkiller) And Antipyretic (fever Reducing) Drug. Paracetamol Reduces Pain By Increasing The Pain Threshold. It Reduces Fever By Acting On The Temperature-regulating Region Of Brain, Resulting In Increased Blood Flow Across The Skin, Sweating And Heat Loss.
Drug Interaction of Paracetamol :Cholestyramine, Metoclopramide And Domperidone May Alter The Effects Of Paracetamol. Use Of Paracetamol With Warfarin May Increase The Risk Of Bleeding. Paracetamol May Increase The Effects Of Chloramphenicol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Paracetamol :Side Effects Of Paracetamol Are Usually Rare, And Include Allergic Reactions Such As Shortness Of Breath, Abnormalities Of Blood Cells, Skin Reddening, Blisters Or Rash, Swollen Facial Features, Or A Runny Nose. Overdose (more Than 4 G In Adults And More Than 2 G In Children) May Cause Severe Liver Damage.

INTERACTIONS OF PARACETAMOL

How Paracetamol will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Paracetamol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Paracetamol

No Studies Found