Medicine : Ostigard Plus Tab

Name:Ostigard Plus Tab
Manufacturer:Zydus Cadila
Generic Use:Celecoxib , Diacerein
Composition:Celecoxib(100 Mg) , Diacerein(50 Mg)
Substitutes:ostigard (100mg) , ostigard plus tab , ostigard (100mg) , ostigard plus tab

Generic ( Celecoxib )

Typical use Of Celecoxib :Pain And Inflammation In Osteoarthritis
Mechanism of action of Celecoxib :Celecoxib Is A Nonsteroidal Antiinflammatory Drug (NSAID) That Is Used To Treat Arthritis, Pain, Menstrual Cramps, And Colonic Polyps. Prostaglandins Are Chemicals That Are Important Contributors To The Inflammation Of Arthritis That Causes Pain, Fever, Swelling And Tenderness. Celecoxib Blocks The Enzyme That Makes Prostaglandins (cyclooxygenase 2), Resulting In Lower Concentrations Of Prostaglandins. As A Consequence, Inflammation And Its Accompanying Pain, Fever, Swelling And Tenderness Are Reduced. Celecoxib Differs From Other NSAIDs In That It Causes Less Inflammation And Ulceration Of The Stomach And Intestine (at Least With Short-term Use) And Does Not Interfere With The Clotting Of Blood.
Drug Interaction of Celecoxib :Co-admin With Fluconazole Increases Plasma Concentrations Of Celecoxib. Avoid Co-admin With Cytochrome P450 2C9 Inhibitors. Increased Risk Of GI Bleeding When Used With Oral Corticosteroids, Anticoagulants Or Alcohol.
Side effects of Celecoxib :Abdominal Pain, Diarrhea, Nausea, Oedema, Dizziness, Headache, Insomnia, Upper Respiratory Tract Infections (URTI); Rash.


How Celecoxib will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Celecoxib will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Celecoxib

No Studies Found

Generic ( Diacerein )

Typical use Of Diacerein :Osteoarthritis.
Mechanism of action of Diacerein :Diacerein Is An Anthraquinone Derivative That Has Been Used In Osteoarthritis. It Is Thought To Act Via Inhibition Of Interleukin-1?.
Drug Interaction of Diacerein :Diacerein Is Known To Interact With Other Drugs Like Aluminium Hydroxide And Oxide, Psyllium Husk. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Diacerein :Nausea, Vomiting, Diarrhea, Rashes, Pruritus, Epigastric Pain, Discoloration Of Urine.


How Diacerein will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Diacerein will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Diacerein

No Studies Found