Medicine : Orthodex

Name:Orthodex
Type:Tablet
Manufacturer:Psychotropics India Ltd
Generic Use:Acetaminophen , Dextropropoxyphene , Ibuprofen
Composition:Acetaminophen(325mg) , Dextropropoxyphene(32.5mg) , Ibuprofen(400mg)
Substitutes:orthodex tab(1) , orthodex , orthodex tab(1) , orthodex , orthodex tab(1) , orthodex


Generic ( Acetaminophen )



Typical use Of Acetaminophen :Analgesic, Antipyretic.
Mechanism of action of Acetaminophen :Acetaminophen Exhibits Analgesic Action By Peripheral Blockage Of Pain Impulse Generation. It Produces Antipyresis By Inhibiting The Hypothalamic Heat-regulating Centre. Its Weak Anti-inflammatory Activity Is Related To Inhibition Of Prostaglandin Synthesis In The CNS.
Drug Interaction of Acetaminophen :Reduced Absorption Of Cholestyramine Within 1 Hr Of Admin. Accelerated Absorption With Metoclopramide. Decreased Effect With Barbiturates, Carbamazepine, Hydantoins, Rifampicin And Sulfinpyrazone. Paracetamol May Increase Effect Of Warfarin.
Side effects of Acetaminophen :Nausea, Allergic Reactions, Skin Rashes, Acute Renal Tubular Necrosis

INTERACTIONS OF ACETAMINOPHEN


How Acetaminophen will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Acetaminophen will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Acetaminophen

No Studies Found






Generic ( Dextropropoxyphene )



Typical use Of Dextropropoxyphene :Mild To Moderate Pain, Opioid Addiction.
Mechanism of action of Dextropropoxyphene :Dextropropoxyphene Is A Centrally Acting, Synthetic Opioid Analgesic Structurally Related To Methadone. It Binds To Opioid Receptors At Many Sites Within The Central Nervous System Affecting Processes For Both The Physiological Perception Of Pain And The Emotional Response To Pain. There Are Multiple Subtypes Of Central And Peripheral Opioid Receptors Each Mediating Therapeutic And/or Adverse Effects Of Opioid Drugs.
Drug Interaction of Dextropropoxyphene :Dextropropoxyphene Is Known To Interact With Other Drugs Like Alcohol, Carbamazepine, Fosphenytoin, Phenobarbitone, Phenytoin (Na), Ritonavir, Warfarin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Dextropropoxyphene :Sinus Tachycardia, Hypotension, Orthostatic Hypotension, Seizures, Dependence, Cholestasis, Psychosis, Sinus Bradycardia, Syncope, Decreased Libido, Biliary Obstruction, Dizziness, Headache, Drowsiness, Nausea, Vomiting, Anorexia, Restlessness, Palpitation, Constipation, Abdominal Pain, Skin Rashes, Blurred Vision, Confusion, Pruritus, Jaundice, Sedation, Malaise, Diaphoresis, Flushing.

INTERACTIONS OF DEXTROPROPOXYPHENE


How Dextropropoxyphene will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Dextropropoxyphene will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Dextropropoxyphene

No Studies Found






Generic ( Ibuprofen )



Typical use Of Ibuprofen :Ibuprofen Is Used For The Relief Of Mild To Moderate Pain Including Pain In The Joints And Muscles, Migraine (one-sided Headache), Dental Pain, Body Pain, Pain During The Menstrual Cycle, As Well As To Treat Fever And Symptoms Of Cold .
Mechanism of action of Ibuprofen :Ibuprofen Belongs To The Group Of Medicines Called Nonsteroidal Anti-inflammatory Drugs. It Is A Pain-killer That Relieves Pain By Blocking Production Of A Certain Natural Substance (prostaglandin) That Is Released In The Body  During Pain.
Drug Interaction of Ibuprofen :Ibuprofen Should Be Used With Caution In Combination With Drugs Such As Corticosteroids, Aspirin, Lithium Drugs, Methotrexate, Cyclosporine, Drugs Used To Treat High Blood Pressure (anti-hypertensive) Or Heart Related Problems (cardiac Glycosides), Blood Thinning Drugs (warfarin), Selective Serotonin-reuptake Inhibitors, Mifepristone, Tacrolimus, Zidovudine, And Quinolone Antibiotics. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ibuprofen :Indigestion, Vomiting, Abdominal Pain, Heart Burn, Diarrhea, Dizziness, Skin Rashes, Sever Allergic Reactions. Heart Patients May Experience Swelling Of Body And Fluid Retention. Overdose May Cause Stomach Or Abdominal Pain And Ringing In The Ears.

INTERACTIONS OF IBUPROFEN


How Ibuprofen will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ibuprofen will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ibuprofen

No Studies Found