Medicine : Oraphipal (50mg)

Name:Oraphipal (50mg)
Manufacturer:Glaxo Smithkline Pharmaceuticals Ltd (allenburys)
Generic Use:Orphenadrine
Composition:Orphenadrine(50 Mg)
Substitutes:orphipal (50mg) , oraphipal (50mg)

Generic ( Orphenadrine )

Typical use Of Orphenadrine :Dystonia, Musculoskeletal Pain, Parkinsonism, Parkinson's Disease, Parkinson's Disease; Drug-induced Extrapyramidal Symptoms, Vertigo.
Mechanism of action of Orphenadrine :Orphenadrine Binds And Inhibits Both Histamine H1 Receptors And NMDA Receptors. It Restores The Motor Disturbances Induced By Neuroleptics, In Particular The Hyperkinesia. The Dopamine Deficiency In The Striatum Increases The Stimulating Effects Of The Cholinergic System. This Stimulation Is Counteracted By The Anticholinergic Effect Of Orphenadrine. It May Have A Relaxing Effect On Skeletal Muscle Spasms And It Has A Mood Elevating Effect.
Drug Interaction of Orphenadrine :Orphenadrine Is Known To Interact With Other Drugs Like Alcohol, Levodopa. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Orphenadrine :Hallucinations, Confusion, Blindness, Chest Tightness, Itching, Breathing Difficulty, Tachycardia, Coma, Seizures, Dry Mouth, Respiratory Depression, Hallucinations, Headache, Drowsiness, Constipation, Dry Mouth, Blurred Vision.


How Orphenadrine will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Orphenadrine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Orphenadrine

No Studies Found