Medicine : Oplone Eye(5ml)

Name:Oplone Eye(5ml)
Type:Drop
Manufacturer:Syntho Pharmaceuticals Pvt Ltd
Generic Use:Ofloxacin , Prednisolone
Composition:Ofloxacin(0.3%w /w) , Prednisolone(1%w /w)
Substitutes:oplone eye(5ml) , oplone eye(5ml)


Generic ( Ofloxacin )



Typical use Of Ofloxacin :To Treat Bacterial Infections Including Urinary Tract Infections, Respiratory Infections , Skin And Soft Tissue Infections, Sexually Transmitted Infections (of Urethra And Cervix) And External Eye Infections (conjuctivitis).
Mechanism of action of Ofloxacin :Ofloxacin Belongs To The Group Of Medicines Called Fluoroquinolone Antibiotics. They Cure The Infection By Inhibiting The DNA Formation And Killing The Bacteria.
Drug Interaction of Ofloxacin :Ofloxacin May Interact With Other Drugs Including Drugs That Are Used To Treat The Abnormal Rate And Rhythm Of Heart (antiarrythmics Viz Quindine, Hydroquindine, Disopyramide, Amiodarone, Sotalol, Dofetilide, Ibutilide), Tricyclic Anti-depressants , Antibiotics (azithromycin) And Some Anti-psychotics. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ofloxacin :When Used As Eye-drops, Side Effects Include Visual Disturbance, Tearing, Mild Stinging, Burning Or Pricking, Irritation, Ocular Discomfort, Inflammation, Redness, Itching, Allergic Reactions In The Eye (including Itchiness Of The Eye And Eyelid), Sensitivity To Light, Eye Swelling. When Used Orally, Side Effects Include Dizziness, Nausea, Allergic Reactions (swelling Of Face, Lips Or Other Parts Of The Body; Rash Or Itching On The Skin; Swelling Of The Mouth, Tongue Or Throat That Can Obstruct The Airways Which May Cause Wheezing, Difficulty Swallowing, Breathing Or Shortness Of Breath; Severe Sudden Life-threatening Allergic Reaction), Swelling Of The Face.

INTERACTIONS OF OFLOXACIN


How Ofloxacin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ofloxacin will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Ofloxacin

No Studies Found






Generic ( Prednisolone )



Typical use Of Prednisolone :Adrenal Insufficiency, Asthma, Blood Malignancies, Connective Tissue Diseases, Liver Diseases, Ocular Diseases, Renal Diseases, Respiratory Disease, Suppression Of Inflammatory And Allergic Disorders.
Mechanism of action of Prednisolone :Glucocorticoids Such As Prednisolone Can Inhibit Leukocyte Infiltration At The Site Of Inflammation, Interfere With Mediators Of Inflammatory Response, And Suppress Humoral Immune Responses. The Antiinflammatory Actions Of Glucocorticoids Are Thought To Involve Phospholipase A2 Inhibitory Proteins, Lipocortins, Which Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes. Prednisolone Reduces Inflammatory Reaction By Limiting The Capillary Dilatation And Permeability Of The Vascular Structures. These Compounds Restrict The Accumulation Of Polymorphonuclear Leukocytes And Macrophages And Reduce The Release Of Vasoactive Kinins.
Drug Interaction of Prednisolone :Rifampin Decreases Blood Levels Of Prednisolone By Increasing Its Breakdown In The Liver. The Dose Of Prednisolone May Need To Be Increased In Order To Avoid Therapeutic Failure. Corticosteroids Have Variable Effects Of Warfarin (Coumadin) Therapy. Coagulation Levels Should Be Monitored More Closely When Anticoagulants Are Combined With Corticosteroids. Estrogens May Increase The Levels Of Prednisolone By Decreasing Its Breakdown. When Estrogens Are Used With Prednisolone, Side Effects Of Prednisolone Should Be Monitored.
Side effects of Prednisolone :On Long Term Use Cushing's Syndrome And Growth Retardation In Childn; Osteoporosis, Fractures. Peptic Ulceration; Glaucoma, Cataract May Occur.

INTERACTIONS OF PREDNISOLONE


How Prednisolone will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Prednisolone will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Prednisolone

No Studies Found