Medicine : Ofelderd
|Manufacturer:||Elder Pharamaceuticals Ltd|
|Generic Use:||Dexamethasone , Hydroxypropylmethylcellulose , Ofloxacin|
|Composition:||Dexamethasone(0.01W/V) , Hydroxypropylmethylcellulose(0.0003W/V) , Ofloxacin(0.003W/V)|
|Substitutes:||ofelderd , ofelderd , ofelderd|
Generic ( Dexamethasone )
|Typical use Of Dexamethasone :||Anorexia In Palliative Care, Congenital Adrenal Hyperplasia, Dyspnoea, Dyspnoea In Palliative Care, Headache Due To Raised Intracranial Pressure In Palliative Care, Nausea And Vomiting (chemotherapy Induced), Pain Due To Nerve Compression In Palliative Care, Raised Intracranial Pressure, Respiratory Distress Syndrome, Shock, Suppression Of Inflammatory And Allergic Disorders.|
|Mechanism of action of Dexamethasone :||Dexamethasone Is A Glucocorticoid Agonist. Unbound Dexamethasone Crosses Cell Membranes And Binds With High Affinity To Specific Cytoplasmic Glucocorticoid Receptors. This Complex Binds To DNA Elements (glucocorticoid Response Elements) Which Results In A Modification Of Transcription And, Hence, Protein Synthesis In Order To Achieve Inhibition Of Leukocyte Infiltration At The Site Of Inflammation, Interference In The Function Of Mediators Of Inflammatory Response, Suppression Of Humoral Immune Responses, And Reduction In Edema Or Scar Tissue. The Antiinflammatory Actions Of Dexamethasone Are Thought To Involve Phospholipase A2 Inhibitory Proteins, Lipocortins, Which Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes.|
|Drug Interaction of Dexamethasone :||Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.|
|Side effects of Dexamethasone :||Glaucoma, Peptic Ulceration, Myopathy, Osteoporosis, Growth Retardation, Aseptic Bone Necrosis, Ocular Hypertension, Subcapsular Cataract, Pancreatic Disturbance, Cushing Like Features, Oedema, Retinal Detachment, Nausea, Vomiting, Insomnia, Nervousness, Nocturia, Increased Appetite, Obesity, Facial Rounding, Fragility Of Skin, Euphoria, Glucose Intolerance.|
INTERACTIONS OF DEXAMETHASONE
How Dexamethasone will impact on Pregnancy ?Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Dexamethasone will impact during lactation(breastfeeding) ?Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.
Medicine & Alcohol use and effect of DexamethasoneNo Studies Found
Generic ( Hydroxypropylmethylcellulose )
|Typical use Of Hydroxypropylmethylcellulose :||Aid In Opthalmic Surgery.|
|Mechanism of action of Hydroxypropylmethylcellulose :||Hydroxypropyl Methylcellulose Is A Nonpyrogenic Viscoelastic Solution That Occupies Space And Protects Tissue. When Used In Anterior Segment Surgeries, It Allows For More Efficient Manipulation With Less Trauma To The Ocular Tissues, Such As The Corneal Endothelium, By Maintaining A Deep Chamber. The Viscoelastic Properties Of Hydroxypropyl Methylcellulose Facilitates Pushing Back The Vitreous Face, Which Prevents The Formation Of A Postoperative Flat Chamber.|
|Drug Interaction of Hydroxypropylmethylcellulose :||Aid In Opthalmic Surgery.|
|Side effects of Hydroxypropylmethylcellulose :||Local Irritation, Iritis, Corneal Edema.|
INTERACTIONS OF HYDROXYPROPYLMETHYLCELLULOSE
How Hydroxypropylmethylcellulose will impact on Pregnancy ?There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Hydroxypropylmethylcellulose will impact during lactation(breastfeeding) ?There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
Medicine & Alcohol use and effect of HydroxypropylmethylcelluloseNo Studies Found
Generic ( Ofloxacin )
|Typical use Of Ofloxacin :||To Treat Bacterial Infections Including Urinary Tract Infections, Respiratory Infections , Skin And Soft Tissue Infections, Sexually Transmitted Infections (of Urethra And Cervix) And External Eye Infections (conjuctivitis).|
|Mechanism of action of Ofloxacin :||Ofloxacin Belongs To The Group Of Medicines Called Fluoroquinolone Antibiotics. They Cure The Infection By Inhibiting The DNA Formation And Killing The Bacteria.|
|Drug Interaction of Ofloxacin :||Ofloxacin May Interact With Other Drugs Including Drugs That Are Used To Treat The Abnormal Rate And Rhythm Of Heart (antiarrythmics Viz Quindine, Hydroquindine, Disopyramide, Amiodarone, Sotalol, Dofetilide, Ibutilide), Tricyclic Anti-depressants , Antibiotics (azithromycin) And Some Anti-psychotics. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.|
|Side effects of Ofloxacin :||When Used As Eye-drops, Side Effects Include Visual Disturbance, Tearing, Mild Stinging, Burning Or Pricking, Irritation, Ocular Discomfort, Inflammation, Redness, Itching, Allergic Reactions In The Eye (including Itchiness Of The Eye And Eyelid), Sensitivity To Light, Eye Swelling. When Used Orally, Side Effects Include Dizziness, Nausea, Allergic Reactions (swelling Of Face, Lips Or Other Parts Of The Body; Rash Or Itching On The Skin; Swelling Of The Mouth, Tongue Or Throat That Can Obstruct The Airways Which May Cause Wheezing, Difficulty Swallowing, Breathing Or Shortness Of Breath; Severe Sudden Life-threatening Allergic Reaction), Swelling Of The Face.|
INTERACTIONS OF OFLOXACIN
How Ofloxacin will impact on Pregnancy ?Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Ofloxacin will impact during lactation(breastfeeding) ?Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.
Medicine & Alcohol use and effect of OfloxacinNo Studies Found