Generic ( Nitazoxanide )

Typical use Of Nitazoxanide :Giardiasis, E.histolytics, T Vaginalis, Cryptosporidium, H. Pylori, Ascaria, H. Nana And Enterobius Vermicularis, Trichuris And Trichura.
Mechanism of action of Nitazoxanide :This Medication Is Taken Up By Diffusion, Is Selectively Absorbed By Anaerobic Bacteria And Sensitive Protozoa. Once Taken Up By Anaerobes, It Is Non-enzymatically Reduced By Reacting With Reduced Ferredoxin, Which Is Generated By Pyruvate Oxido-reductase. Many Of The Reduced Nitroso Intermediates Will Form Sulfinamides And Thioether Linkages With Cysteine Bearing Enzymes Deactivating These Critical Enzymes. As Many As 150 Separate Enzymes Are Affected.
Drug Interaction of Nitazoxanide :Nitazoxanide Is Known To Interact With Other Drugs Like Warfarin (Na).
Side effects of Nitazoxanide :Nausea, Stomach Upset, Skin Rash, Acute Toxicity.


How Nitazoxanide will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Nitazoxanide will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Nitazoxanide

No Studies Found